Alkaline phosphatase.macrohepatic/Alkaline phosphatase.total

ChemistryAlso known as: ALP Macrohepatic CFr SerPl%

Measures the fraction of alkaline phosphatase from macrophages in the liver as a ratio to total ALP.

Normal Range

Consult your provider

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

This test helps pinpoint liver-specific causes of elevated alkaline phosphatase, improving diagnostic accuracy for chronic liver disease and cirrhosis.

Overview

This test measures the fraction of alkaline phosphatase (ALP) enzyme that comes from macrophages in the liver—a specific subtype called macrohepatic ALP. When expressed as a ratio to total ALP, it helps identify the source of elevated alkaline phosphatase. Elevated macrohepatic ALP may indicate liver disease, cirrhosis, or chronic inflammatory liver conditions. This specialized test provides diagnostic detail beyond routine ALP testing and helps differentiate liver disorders from other conditions causing ALP elevation.