Caffeine

ToxicologyAlso known as: 1,3,7-Trimethylxanthineug/mL

Measures caffeine metabolites in serum or plasma to assess recent caffeine consumption.

Normal Range
Consult your provider
ug/mL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Caffeine testing helps evaluate intake when restricting for medical reasons or investigating symptoms potentially related to caffeine sensitivity or toxicity.

Overview

This urine test measures caffeine metabolites to detect caffeine consumption. It may be used in clinical settings to assess caffeine intake, monitor compliance with caffeine restriction (as recommended for certain heart conditions or during pregnancy), or evaluate unexpected symptoms. Caffeine levels in urine reflect recent consumption from coffee, tea, energy drinks, and medications. This test provides objective evidence of caffeine exposure when patient history is unclear.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

3422-3Primary
Caffeine [Mass/volume] in Serum or Plasma
ug/mL
3424-9
Caffeine [Mass/volume] in Urine
ug/mL
4150-9
Caffeine [Mass] of Dose
mg
3423-1
Caffeine [Presence] in Urine
25361-7
Caffeine [Moles/volume] in Serum or Plasma
umol/L
60290-4
Caffeine [Moles/volume] in Specimen
umol/L
29211-0
Caffeine [Mass/volume] in Body fluid
mg/L
40416-0
Caffeine [Presence] in Gastric fluid
43829-1
Caffeine [Presence] in Specimen

Available Lab Tests

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