Gastrin

ChemistryAlso known as: Fasting GastrinAlso known as: Serum Gastrinpmol/L

Measures gastrin hormone levels to assess stomach acid regulation.

Normal Range

18 – 115 pmol/L

pmol/L

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Elevated gastrin indicates gastrinoma or severe acid disease causing ulcers and digestive distress. Early diagnosis prevents complications and guides medical or surgical treatment.

Understanding Your Results

Normal Range

18 – 115 pmol/L

Overview

Gastrin is a hormone produced by stomach cells that stimulates acid secretion for digestion. Elevated fasting gastrin levels may indicate a gastrin-secreting tumor (gastrinoma), severe acid reflux disease, or atrophic gastritis. This test requires fasting and is often combined with a stomach acid pH test for accurate interpretation. Elevated gastrin causes severe ulcers and digestive symptoms. Diagnosis enables targeted treatment to control acid production.

Research & Evidence

19 publications

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Gastrin for the treatment of acute graft-versus-host disease of the stomach.

Blood · 2026

PMID: 41511880Other

[Clinical efficacy of abdominal acupuncture therapy combined with transcranial direct current stimulation on post-stroke depression and the influence on the levels of autophagy-related proteins].

Zhongguo Zhen Jiu · 2026

PMID: 41987434

Insulinoma complicated with hypergastrinemia in a subject with type 2 diabetes mellitus: a case report.

Diabetol Int · 2026

PMID: 41809843

Extracellular signalling regulates gastrin transcription through site-specific phosphorylation and nuclear redistribution of Menin.

bioRxiv · 2026

PMID: 41993411

A case of multiple type I endocrine neoplasia with gastrin-producing and glucagon-producing tumors successfully resected 18 years after insulinoma surgery.

Clin J Gastroenterol · 2026

PMID: 41945253

Novel Theranostic Targets for Prostate Cancer Beyond Prostate-Specific Membrane Antigen.

PET Clin · 2026

PMID: 41951504

Hederagenin suppresses inflammation-cancer transformation in chronic atrophic gastritis by modulating glycolysis through the mTOR/HIF-1α axis.

Eur J Pharmacol · 2026

PMID: 41932673

Potassium-Competitive Acid Blocker-Associated Gastric Hyperplastic Polyps With Severe Bleeding: A Case Series.

DEN Open · 2026

PMID: 41988636

Assessment of Circulating Neuroendocrine Tumor Markers at Prostate Cancer Diagnosis: An Investigation of Prostate Cancer With Neuroendocrine Features.

Prostate · 2026

PMID: 41995698

Modular Nanotransporters Containing Anti-PSMA Nanobodies Are Able to Penetrate into the Nuclei of Prostate Cancer Cells.

Dokl Biochem Biophys · 2026

PMID: 42010078

Research data from MEDLINE/PubMed · 19 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

2333-3Primary

Gastrin [Mass/volume] in Serum or Plasma

pg/mL

15072-2

Gastrin [Moles/volume] in Serum or Plasma

pmol/L

Available Lab Tests

Order tests that measure this biomarker

Gastrin Test