Hemoglobin E

HematologyAlso known as: HbEN/A

The presence or absence of the hemoglobin E genetic variant in your red blood cells.

Normal Range

Consult your provider

N/A

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Detecting hemoglobin E helps identify inherited blood disorders that can cause anemia, allows for genetic counseling, and informs family planning decisions.

Overview

Hemoglobin E is an abnormal hemoglobin variant resulting from a genetic mutation in the beta-globin chain. This qualitative test detects the presence or absence of hemoglobin E through blood electrophoresis. Individuals with hemoglobin E trait carry one copy of the mutation and typically have mild or no symptoms. Those with hemoglobin E disease (two copies) may experience hemolytic anemia, fatigue, and jaundice. This test is important for genetic screening, particularly in populations where the mutation is more common.