Lactate dehydrogenase

ChemistryAlso known as: LdAlso known as: LDHN/A

Detects lactate dehydrogenase enzyme in serum or plasma, indicating possible tissue damage.

Normal Range

Consult your provider

N/A

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Elevated urine LDH may indicate kidney damage, urinary tract infection, or muscle injury. Results help assess kidney function and detect urinary system abnormalities.

Overview

Lactate dehydrogenase (LDH) is an enzyme found throughout your body that helps break down glucose for energy. When LDH appears in urine, it may indicate kidney damage, urinary tract infection, or muscle injury. Elevated urine LDH can also suggest hemolysis (breakdown of red blood cells) or certain cancers affecting the urinary system. This test is less commonly used than blood LDH but provides additional clinical information when kidney or muscle damage is suspected.

Related Health Conditions

Conditions where Lactate dehydrogenase is commonly tested

Malignant tumour

Related Health Goals

Screen for Cancer Risk

Research & Evidence

100 publications

Sort:

MPN-FIT: a randomized controlled pilot trial of supervised exercise in myeloproliferative neoplasms.

Blood Adv · 2026

PMID: 41499761Other

Indirect treatment comparison of iptacopan versus pegcetacoplan for patients with paroxysmal nocturnal hemoglobinuria and residual anemia despite C5 inhibitor treatment.

J Comp Eff Res · 2026

PMID: 41852168

Gliclazide Enhances Exercise Performance and Recovery of Muscle Strength in Healthy Trained Individuals: A Randomized Controlled Trial.

Eur J Sport Sci · 2026

PMID: 41818607

Prognostic factors for mortality in age-stratified elderly sepsis patients: A retrospective cohort study based on the MIMIC-IV database.

Medicine (Baltimore) · 2026

PMID: 41961689

Serum CEACAM6 and CEACAM8 as predictors of poor outcome in pediatric Mycoplasma pneumoniae pneumonia: A single-center prospective cohort study.

Medicine (Baltimore) · 2026

PMID: 41961692

Predictive value of the lactate dehydrogenase to albumin ratio for coronary artery lesions and IVIG resistance in Kawasaki disease.

BMC Pediatr · 2026

PMID: 41942965

LDH isozymes as targets for cancer therapy.

J Enzyme Inhib Med Chem · 2026

PMID: 41837490

Effects of protein phosphorylation on lactate dehydrogenase activity glycolysis in postmortem Yanbian yellow cattle muscle.

Int J Biol Macromol · 2026

PMID: 41946405

COVID-19 and cardiovascular outcomes in patients with pre-existing hypertension.

J Hum Hypertens · 2026

PMID: 41957521

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review).

Exp Ther Med · 2026

PMID: 41929534

Research data from MEDLINE/PubMed · 100 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

14805-6Primary

Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Pyruvate to lactate reaction

U/L

14803-1

Lactate dehydrogenase [Enzymatic activity/volume] in Body fluid by Lactate to pyruvate reaction

U/L

60017-1

Lactate dehydrogenase [Enzymatic activity/volume] in Body fluid by Pyruvate to lactate reaction

U/L

14804-9

Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

U/L

17041-5

Lactate dehydrogenase [Presence] in Urine

2534-6

Lactate dehydrogenase [Enzymatic activity/volume] in Urine

U/L

68387-0

Lactate dehydrogenase [Enzymatic activity/volume] in Peritoneal fluid by Lactate to pyruvate reaction

U/L

60019-7

Lactate dehydrogenase [Enzymatic activity/volume] in Pericardial fluid by Lactate to pyruvate reaction

U/L

68453-0

Lactate dehydrogenase [Enzymatic activity/volume] in Synovial fluid by Lactate to pyruvate reaction

U/L

60024-7

Lactate dehydrogenase [Enzymatic activity/volume] in Cerebral spinal fluid by Lactate to pyruvate reaction

U/L

60020-5

Lactate dehydrogenase [Enzymatic activity/volume] in Peritoneal fluid by Pyruvate to lactate reaction

U/L

60021-3

Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Pyruvate to lactate reaction

U/L

60022-1

Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

U/L

32324-6

Lactate dehydrogenase [Enzymatic activity/volume] in Specimen

U/L

81430-1

Lactate dehydrogenase [Enzymatic activity/volume] in Peritoneal dialysis fluid by Lactate to pyruvate reaction

U/L

14403-0

Lactate dehydrogenase [Enzymatic activity/volume] in Gastric fluid

U/L

2527-0

Lactate dehydrogenase [Enzymatic activity/volume] in Amniotic fluid

U/L

47678-8

Lactate dehydrogenase [Enzymatic activity/volume] in 24 hour Urine

[IU]/L

47863-6

Lactate dehydrogenase [Enzymatic activity/time] in 24 hour Urine

U/(24.h)

57664-5

Lactate dehydrogenase [Enzymatic activity/volume] in Semen

U/mL

5921-2

Lactate dehydrogenase [Enzymatic activity/volume] in Dialysis fluid

U/L

60018-9

Lactate dehydrogenase [Enzymatic activity/volume] in Pericardial fluid by Pyruvate to lactate reaction

U/L

60023-9

Lactate dehydrogenase [Enzymatic activity/volume] in Cerebral spinal fluid by Pyruvate to lactate reaction

U/L

68452-2

Lactate dehydrogenase [Enzymatic activity/volume] in Synovial fluid by Pyruvate to lactate reaction

U/L

11053-6

Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood Cells

U/mL{RBCs}

Available Lab Tests

Order tests that measure this biomarker

Find Specialists

Doctors who commonly order this test

Internal Medicine

Medical Oncology