Leptin

ChemistryAlso known as: Obese proteinAlso known as: Ob proteinng/mL

Measures the appetite-regulating hormone produced by fat cells.

Normal Range
4 – 6 ng/mL
ng/mL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Leptin imbalance affects hunger, metabolism, and weight regulation. Abnormal levels may indicate metabolic dysfunction, hypothalamic disorders, or resistance to leptin's effects.

Understanding Your Results

Normal Range

4 – 6 ng/mL

Overview

Leptin is a hormone produced by fat cells that regulates appetite and energy expenditure. This test measures blood leptin levels, which generally correlate with body fat mass. Leptin tells your brain when you are full and helps regulate metabolism. Abnormally low leptin can indicate insufficient fat stores or hypothalamic dysfunction, while elevated leptin (often with obesity) may indicate leptin resistance, where the body doesn't respond properly to the hormone. Leptin levels help assess metabolic and appetite regulation.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

21365-2Primary
Leptin [Mass/volume] in Serum or Plasma
ng/mL

Available Lab Tests

Order tests that measure this biomarker