Pristanate

Pristanate is another branched-chain fatty acid metabolite measured in blood. Like phytanate, elevated pristanate levels suggest peroxisomal disorders affecting fatty acid metabolism, such as Refsum disease or related conditions. Pristanate and phytanate are often measured together as markers of peroxisomal dysfunction. These rare genetic disorders cause accumulation of these fatty acids, leading to progressive neurological symptoms including peripheral neuropathy and ataxia.