Tiglylglycine

Tiglylglycine is a urinary organic acid metabolite that indicates a specific pattern of fatty acid metabolism dysfunction. Its presence in urine suggests possible fatty acid oxidation disorders, particularly short-chain acyl-CoA dehydrogenase (SCAD) deficiency or related metabolic conditions. These rare genetic disorders impair the body's ability to break down certain fats for energy, potentially causing fatigue, muscle weakness, or developmental delays. Detecting tiglylglycine helps identify these serious metabolic disorders requiring specialized management.