ALS8 - amyotrophic lateral sclerosis type 8

disorder

SNOMED 1204350002CUI C1837728

Overview

ALS8 - amyotrophic lateral sclerosis type 8 is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Postural tremor

Always present (100%)HP:0002174

Muscle fasciculation

Very frequent (80-99%)HP:0002380

Muscle spasm

Very frequent (80-99%)HP:0003394

Proximal limb muscle weakness

Very frequent (80-99%)HP:0003701

Bulbar signs

Frequent (30-79%)HP:0002483

Corticospinal signs

Frequent (30-79%)HP:0007256

Deglutition disorder

Frequent (30-79%)HP:0002015

Distal limb muscle weakness due to peripheral neuropathy

Frequent (30-79%)HP:0002460

Distal muscle atrophy, upper and lower limbs

Frequent (30-79%)HP:0003693

Loss of ambulation

Frequent (30-79%)HP:0002505

Symmetrical, proximal limb muscle atrophy

Frequent (30-79%)HP:0007126

Amyotrophic lateral sclerosis

HP:0007354

Areflexia

HP:0001284

Cognitive deficits

Excluded (<1%)HP:0100543

Difficulty articulating speech

HP:0001260

Muscle atrophy, neurogenic

HP:0003202

Neuronal loss in CNS

HP:0002529

Progressive muscle weakness

HP:0003323

Pyramidal tract disease

HP:0002062

Related Conditions

Autosomal dominant hereditary disorder(parent)

Degenerative disorder(parent)

Hereditary disorder of nervous system(parent)

Amyotrophic lateral sclerosis(parent)

Chronic nervous system disease(parent)

Quick Facts

SNOMED CT: 1204350002
UMLS CUI: C1837728
Fully Specified Name: Amyotrophic lateral sclerosis type 8 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 19

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.