Overview
Antisynthetase syndrome is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Autoimmunity
Very frequent (80-99%)HP:0002960
Chest discomfort
Very frequent (80-99%)HP:0100749
Coughing
Very frequent (80-99%)HP:0012735
Interstitial pulmonary disease
Very frequent (80-99%)HP:0006530
Muscle inflammation
Very frequent (80-99%)HP:0100614
Muscle pain
Very frequent (80-99%)HP:0003326
Muscle weakness
Very frequent (80-99%)HP:0001324
Pulmonary fibrosis
Very frequent (80-99%)HP:0002206
Respiratory insufficiency
Very frequent (80-99%)HP:0002093
Abnormal electromyography finding
Frequent (30-79%)HP:0003457
Anti-alanyl-tRNA synthetase antibody positivity
Frequent (30-79%)HP:0034145
Anti-aminoacyl-tRNA synthetase antibody positivity
Frequent (30-79%)HP:0034147
Anti-asparaginyl-tRNA synthetase antibody positivity
Frequent (30-79%)HP:0034151
Anti-cytosolic-5-nucleotidase-1A antibody positivity
Frequent (30-79%)HP:0034153
Anti-glycyl tRNA-synthetase antibody positivity
Frequent (30-79%)HP:0034146
Anti-Jo-1 antibody positivity
Frequent (30-79%)HP:0034152
Anti-OJ antibody positivity
Frequent (30-79%)HP:0034148
Anti-PL-7 antibody positivity
Frequent (30-79%)HP:0034143
Anti-tyrosyl-tRNA synthetase antibody positivity
Frequent (30-79%)HP:0034150
Arthralgias
Frequent (30-79%)HP:0002829
Edema
Frequent (30-79%)HP:0000969
Elevated serum creatine phosphokinase
Frequent (30-79%)HP:0003236
Joint inflammation
Frequent (30-79%)HP:0001369
Keratoconjunctivitis sicca
Frequent (30-79%)HP:0001097
Lack of skin elasticity
Frequent (30-79%)HP:0100679
Muscular hypotonia
Frequent (30-79%)HP:0001252
Panting
Frequent (30-79%)HP:0002094
Phenylanyl-t-RNA synthetase alpha antibody positivity
Frequent (30-79%)HP:0034149
Pyrexia
Frequent (30-79%)HP:0001945
Raynaud phenomenon
Frequent (30-79%)HP:0030880
Quick Facts
- SNOMED CT
- 445187004
- UMLS CUI
- C5959873
- Fully Specified Name
- Antisynthetase syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.