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Autosomal dominant polycystic kidney disease

disorder
SNOMED 765330003CUI C0085413

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Clinical Trials

7
Total Trials
3
Recruiting
2
With Results

Recent Trials

HYDROchlorothiazide to PROTECT Polycystic Kidney Disease Patients and Improve Their Quality of Life

NCT05373264Phase 3Recruiting300 enrolled

Statin Therapy in Patients With Early Stage ADPKD

NCT03273413Phase 4Active Not Recruiting150 enrolled

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD)

NCT06391450Phase 4Active Not Recruiting44 enrolled

Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease

NCT00414440Phase 4Completed431 enrolled

Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease

NCT03949894Phase 4Completed118 enrolled
View all 7 trials on ClinicalTrials.gov

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Cystic kidney disease
Very frequent (80-99%)HP:0000107
Decreased glomerular filtration rate
Very frequent (80-99%)HP:0012213
Increased creatinine
Very frequent (80-99%)HP:0003259
Liver cysts
Very frequent (80-99%)HP:0001407
Renal failure
Very frequent (80-99%)HP:0000083
Abnormal urinary electrolyte concentration
Frequent (30-79%)HP:0012591
Albuminuria
Frequent (30-79%)HP:0012592
End-stage renal disease
Frequent (30-79%)HP:0003774
High blood pressure
Frequent (30-79%)HP:0000822
High urine occult blood
Frequent (30-79%)HP:0000790
Kidney pain
Frequent (30-79%)HP:0030157
Mitral regurgitation, mild
Frequent (30-79%)HP:0001653
Progressive renal failure
Frequent (30-79%)HP:0012622
Abnormality of the systemic arterial tree
Occasional (5-29%)HP:0011004
Aortic root dilatation
Occasional (5-29%)HP:0002616
Brain aneurysm
Occasional (5-29%)HP:0004944
Ca2+ oxalate urolithiasis
Occasional (5-29%)HP:0008672
Enlarged kidney
Occasional (5-29%)HP:0000105
Fluid-filled sac located in membrane surrounding brain or spinal cord
Occasional (5-29%)HP:0100702
Mitral valve prolapse
Occasional (5-29%)HP:0001634
Multiple pancreatic cysts
Occasional (5-29%)HP:0001737
Polycystic liver disease
Occasional (5-29%)HP:0006557
Pyelonephritis
Occasional (5-29%)HP:0012330
Reduced sperm motility
Occasional (5-29%)HP:0012207
Repeated bladder infections
Occasional (5-29%)HP:0000010
Uric acid stones
Occasional (5-29%)HP:0000791
Cerebral saccular aneurysm
Very rare (1-4%)HP:0007029
Pituitary somatotropinoma
Very rare (1-4%)HP:0011760
Colon diverticula
HP:0002253
Polycystic kidneys
HP:0000113

Related Conditions

PKD2 - Polycystic kidney disease 2(child)
Adult type polycystic kidney disease type 1(child)
Autosomal dominant polycystic kidney disease in childhood(child)
Autosomal dominant polycystic kidney disease type 1 with tuberous sclerosis(child)
Multinodular goiter, cystic kidney, polydactyly syndrome(child)
Autosomal dominant hereditary disorder(parent)
Congenital cystic kidney disease(parent)
Hereditary nephropathy(parent)

Quick Facts

SNOMED CT
765330003
UMLS CUI
C0085413
Fully Specified Name
Autosomal dominant polycystic kidney disease (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Clinical Trials
7
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.