Autosomal dominant spastic paraplegia type 38

disorder

SNOMED 783622001CUI C2676732

Overview

Autosomal dominant spastic paraplegia type 38 is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Cavus foot

Very frequent (80-99%)HP:0001761

Degeneration of the lateral corticospinal tracts

Very frequent (80-99%)HP:0002314

Extensor plantar responses

Very frequent (80-99%)HP:0003487

Increased reflexes

Very frequent (80-99%)HP:0001347

Progressive spastic paraplegia

Very frequent (80-99%)HP:0007020

Spastic walk

Very frequent (80-99%)HP:0002064

Spasticity of lower limb

Very frequent (80-99%)HP:0002061

Thenar muscle atrophy

Very frequent (80-99%)HP:0003393

Abnormal electromyography finding

Frequent (30-79%)HP:0003457

Amyotrophy of ankle musculature

Frequent (30-79%)HP:0009031

Distal muscle weakness in lower limbs

Frequent (30-79%)HP:0009053

First dorsal interossei muscle atrophy

Frequent (30-79%)HP:0003426

First dorsal interossei muscle weakness

Frequent (30-79%)HP:0003392

Spinal cord lesion

Frequent (30-79%)HP:0100561

Thenar muscle weakness

Frequent (30-79%)HP:0003427

Distal sensory loss, especially vibratory sense

Occasional (5-29%)HP:0002166

Frontotemporal cerebral atrophy

Occasional (5-29%)HP:0006892

Inability to heel walk

Occasional (5-29%)HP:0009027

Intellectual impairment

Occasional (5-29%)HP:0100543

Distal limb muscle weakness due to peripheral neuropathy

HP:0002460

Distal muscle atrophy, upper and lower limbs

HP:0003693

Lower limb muscle weakness

HP:0007340

Spastic paraplegia

HP:0001258

Related Conditions

Autosomal dominant complex hereditary spastic paraplegia(parent)

Quick Facts

SNOMED CT: 783622001
UMLS CUI: C2676732
Fully Specified Name: Autosomal dominant spastic paraplegia type 38 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 23

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.