Overview
Charcot-Marie-Tooth disease type 4G is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Lower limb degeneration
Always present (100%)HP:0008944
Abnormality of the feet
Very frequent (80-99%)HP:0001760
Absent deep tendon reflexes
Very frequent (80-99%)HP:0001284
Axonal neuropathy
Very frequent (80-99%)HP:0003477
Decreased distal sensory nerve action potential
Very frequent (80-99%)HP:0007230
Decreased motor nerve conduction velocity
Very frequent (80-99%)HP:0003431
Demyelinating peripheral neuropathy
Very frequent (80-99%)HP:0007108
Distal muscle weakness in lower limbs
Very frequent (80-99%)HP:0009053
Distal sensory impairment of all modalities
Very frequent (80-99%)HP:0003409
Impaired vibratory sensation
Very frequent (80-99%)HP:0002495
Loss of distal sensation
Very frequent (80-99%)HP:0002936
Motor conduction block
Very frequent (80-99%)HP:0012078
Peripheral demyelination
Very frequent (80-99%)HP:0011096
Abnormal hands
Frequent (30-79%)HP:0001155
Amyotrophy involving the upper limbs
Frequent (30-79%)HP:0009129
Cavus foot
Frequent (30-79%)HP:0001761
Distal muscle atrophy, upper and lower limbs
Frequent (30-79%)HP:0003693
Distal upper limb muscle weakness
Frequent (30-79%)HP:0008959
Fetal foot inversion
Frequent (30-79%)HP:0001762
Gait disturbance
Frequent (30-79%)HP:0001288
Loss of tactile sensation
Frequent (30-79%)HP:0010830
Lower limb amyotrophy
Frequent (30-79%)HP:0007210
Proximal limb muscle weakness
Frequent (30-79%)HP:0003701
Abnormality of balance
Occasional (5-29%)HP:0002141
Cobb angle greater than ten degrees
Occasional (5-29%)HP:0002650
Impaired pain sensation
Occasional (5-29%)HP:0007328
Loss of ambulation
Occasional (5-29%)HP:0002505
Pes valgus
Occasional (5-29%)HP:0008081
Dysphonia
Very rare (1-4%)HP:0001618
Eye drop
Very rare (1-4%)HP:0000508
Related Conditions
Quick Facts
- SNOMED CT
- 715799004
- UMLS CUI
- C1854449
- Fully Specified Name
- Charcot-Marie-Tooth disease type 4G (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.