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Fibrous dysplasia of bone

disorder
SNOMED 10623005CUI C0259779

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Fibrous Dysplasia of Bone" from the MEDLINE/PubMed database.

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Clinical characteristics of simple bone cyst associated within florid cemento-osseous dysplasia: a meta-analysis.
[object Object], [object Object], [object Object] et al. · Med Oral Patol Oral Cir Bucal · 2025
PMID: 40818140Meta-AnalysisFull text (PMC)
Clinical and radiologic outcomes of dental implants in cemento-osseous dysplasia: a systematic review and retrospective case series.
[object Object], [object Object], [object Object] et al. · BMC Oral Health · 2025
PMID: 40618148Meta-AnalysisFull text (PMC)
Treatment indications for symptomatic versus asymptomatic florid cemento-osseous dysplasia in adult patients: a systematic review.
[object Object], [object Object], [object Object] et al. · Oral Surg Oral Med Oral Pathol Oral Radiol · 2024
PMID: 39306516Meta-Analysis
Efficacy of antiresorptive agents in fibrous dysplasia and McCune Albright syndrome, a systematic review and meta-analysis.
[object Object], [object Object], [object Object] · Rev Endocr Metab Disord · 2023
PMID: 37632645Meta-Analysis
Fibrous dysplasia animal models: A systematic review.
[object Object], [object Object], [object Object] et al. · Bone · 2022
PMID: 34875396Meta-Analysis
Risk of developing spontaneous MRONJ in fibrous dysplasia patients treated with bisphosphonates: a systematic review of the literature.
[object Object], [object Object], [object Object] · Quintessence Int · 2022
PMID: 35674165Meta-Analysis
Surgical management of syndromic versus non-syndromic craniofacial fibrous dysplasia: a systematic review and meta-analysis.
[object Object], [object Object] · Br J Oral Maxillofac Surg · 2022
PMID: 35817637Meta-Analysis
Malignant transformation of craniofacial fibrous dysplasia: a systematic review of overall survival.
[object Object], [object Object], [object Object] et al. · Neurosurg Rev · 2020
PMID: 30809751Meta-Analysis
Magnetic resonance imaging characteristics in patients with histopathologically proven fibrous dysplasia-a systematic review.
[object Object], [object Object], [object Object] · Skeletal Radiol · 2020
PMID: 32040603Meta-AnalysisFull text (PMC)

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Fibrous dysplasia of the bones
Always present (100%)HP:0010734
Abnormal axial skeleton morphology
Very frequent (80-99%)HP:0009121
Abnormal bone structure
Very frequent (80-99%)HP:0003330
Abnormality of the skull bones
Very frequent (80-99%)HP:0000929
Breakdown of bone
Very frequent (80-99%)HP:0002797
Limb anomaly
Very frequent (80-99%)HP:0040064
Abnormal mandible morphology
Frequent (30-79%)HP:0000277
Abnormality of the thighbone
Frequent (30-79%)HP:0002823
Anomaly of facial skeleton
Frequent (30-79%)HP:0011821
Anomaly of the zygomatic bone
Frequent (30-79%)HP:0010668
Bone pain
Frequent (30-79%)HP:0002653
Bowed long bones
Frequent (30-79%)HP:0006487
Cortical irregularity
Frequent (30-79%)HP:0005731
Elevated alkaline phosphatase
Frequent (30-79%)HP:0003155
Hypophosphataemia
Frequent (30-79%)HP:0002148
Limp
Frequent (30-79%)HP:0031955
Malformation of the maxilla
Frequent (30-79%)HP:0000326
Patchy reduction of bone mineral density
Frequent (30-79%)HP:0010657
Pathologic fracture
Frequent (30-79%)HP:0002756
Thin cortices
Frequent (30-79%)HP:0002753
Weak and soft bones
Frequent (30-79%)HP:0002748
Abnormal clavicles
Occasional (5-29%)HP:0000889
Abnormal humerus morphology
Occasional (5-29%)HP:0031095
Abnormal lumbar spine morphology
Occasional (5-29%)HP:0100712
Abnormal morphology of the radius
Occasional (5-29%)HP:0002818
Abnormal morphology of ulna
Occasional (5-29%)HP:0040071
Abnormal occipital bone morphology
Occasional (5-29%)HP:0012294
Abnormal parietal bone morphology
Occasional (5-29%)HP:0002696
Abnormal pelvis bone morphology
Occasional (5-29%)HP:0040163
Abnormal temporal bone morphology
Occasional (5-29%)HP:0009911

Quick Facts

SNOMED CT
10623005
UMLS CUI
C0259779
Fully Specified Name
Fibrous dysplasia of bone (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.