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Juvenile neuronal ceroid lipofuscinosis

disorder
SNOMED 61663001CUI C0751383

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Decreased visual acuity
Always present (100%)HP:0007663
Enlarged lysosomal vacuoles in lymphocytes
Always present (100%)HP:0001922
Fingerprint profiles ultrastructurally
Always present (100%)HP:0003208
Generalized tonic-clonic seizure (without specification of onset)
Always present (100%)HP:0002069
Loss of ambulation
Always present (100%)HP:0002505
Parkinsonian disease
Always present (100%)HP:0001300
Progressive visual loss
Always present (100%)HP:0000529
Psychomotor deterioration
Always present (100%)HP:0002361
Retinal degeneration
Always present (100%)HP:0000546
Abolished electroretinogram
HP:0000550
Anxiety disease
HP:0000739
Cataract
HP:0000518
Cerebellar signs
HP:0001317
Difficulty articulating speech
HP:0001260
Dull intelligence
HP:0001249
Epilepsy
HP:0001250
Extrapyramidal dysfunction
HP:0002071
Glaucoma
HP:0000501
Increased extraneuronal autofluorescent lipopigment
HP:0003463
Intracellular curvilinear profiles on ultrastructural analysis
HP:0003205
Involuntary jerking movements
HP:0001336
Legal blindness
HP:0000618
Neuronal lipopigments
HP:0002074
Optic atrophy
HP:0000648
Pigmented macular degeneration
HP:0000608
Progressive dementia
HP:0000726
Psychosis
HP:0000709
Retinitis pigmentosa
HP:0000510
Supratentorial atrophy
HP:0002059
Symmetric, concentric, hypertrophic cardiomyopathy
HP:0005157

Quick Facts

SNOMED CT
61663001
UMLS CUI
C0751383
Fully Specified Name
Juvenile neuronal ceroid lipofuscinosis (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.