Overview
By MedlinePlus, National Library of Medicine
Courtesy of the National Library of Medicine. Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Difficulty finding words
Very frequent (80-99%)HP:0002381
Electrical status epilepticus during slow-wave sleep
Very frequent (80-99%)HP:0031491
Epilepsy
Very frequent (80-99%)HP:0001250
Interictal EEG abnormality
Very frequent (80-99%)HP:0025373
Language impairment
Very frequent (80-99%)HP:0002463
Loss of speech
Very frequent (80-99%)HP:0002371
Speech dyspraxia
Very frequent (80-99%)HP:0011098
Spoken word recognition deficit
Very frequent (80-99%)HP:0030391
Autism spectrum disorder
Frequent (30-79%)HP:0000729
Behavioral changes
Frequent (30-79%)HP:0000708
Bilateral tonic-clonic seizure with generalized onset
Frequent (30-79%)HP:0025190
Childhood attention deficit/hyperactivity disorder
Frequent (30-79%)HP:0007018
Decreased body height
Frequent (30-79%)HP:0004322
EEG with centrotemporal focal spike waves
Frequent (30-79%)HP:0012557
EEG with frontal focal spikes
Frequent (30-79%)HP:0012015
EEG with generalized epileptiform discharges
Frequent (30-79%)HP:0011198
EEG with temporal focal spikes
Frequent (30-79%)HP:0012018
Generalized non-motor (absence) seizure
Frequent (30-79%)HP:0002121
Localized motor seizures
Frequent (30-79%)HP:0011153
Mental deterioration in childhood
Frequent (30-79%)HP:0002376
Muscular hypotonia
Frequent (30-79%)HP:0001252
Psychomotor development deficiency
Frequent (30-79%)HP:0001263
Small skull present at birth
Frequent (30-79%)HP:0011451
Social and occupational deterioration
Frequent (30-79%)HP:0007086
Speech articulation difficulties
Frequent (30-79%)HP:0009088
Speech delay
Frequent (30-79%)HP:0000750
Aggression
Occasional (5-29%)HP:0000718
Atypical absence
Occasional (5-29%)HP:0007270
Cavus foot
Occasional (5-29%)HP:0001761
Complex partial seizures
Occasional (5-29%)HP:0002384
Quick Facts
- SNOMED CT
- 230438007
- UMLS CUI
- C0282512
- Fully Specified Name
- Landau-Kleffner syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.