Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Hoarse cry
Always present (100%)HP:0001615
Wing-shaped conjunctiva
Always present (100%)HP:0034363
Open skin sore
Very frequent (80-99%)HP:0200042
Subglottic stenosis
Very frequent (80-99%)HP:0001607
Abnormality of the periungual region
Frequent (30-79%)HP:0100803
Blister
Frequent (30-79%)HP:0008066
Bullae of oral mucosa
Frequent (30-79%)HP:0200097
Corneal erosion
Frequent (30-79%)HP:0200020
Corneal ulcerations
Frequent (30-79%)HP:0012804
Decreased width of tooth
Frequent (30-79%)HP:0000691
Delayed eruption of teeth
Frequent (30-79%)HP:0000684
Dysplasia of tooth enamel
Frequent (30-79%)HP:0006297
Dystrophic nails
Frequent (30-79%)HP:0008404
Exuberant granulation tissue
Frequent (30-79%)HP:6000956
Eyelid adhesion to globe of eye
Frequent (30-79%)HP:0430007
Fragile skin
Frequent (30-79%)HP:0001030
Husky voice
Frequent (30-79%)HP:0001609
Inspiratory stridor
Frequent (30-79%)HP:0005348
Rotting teeth
Frequent (30-79%)HP:0000670
Skin erosion
Frequent (30-79%)HP:0200041
Abnormality of the vocal cords
Occasional (5-29%)HP:0008777
Hypochromic, microcytic anaemia
Occasional (5-29%)HP:0004840
Impaired vision
Occasional (5-29%)HP:0000505
Nasal hemorrhage
Occasional (5-29%)HP:0000421
Amelogenesis imperfecta
HP:0000705
Recurrent loss of toenails and fingernails
HP:0008390
Weak cry
HP:0001612
Quick Facts
- SNOMED CT
- 722675000
- UMLS CUI
- C1328355
- Fully Specified Name
- Laryngo-onycho-cutaneous syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 27
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.