Multiple endocrine neoplasia, type 1

disorder

SNOMED 30664006CUI C0025267

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Angiofibromas

Very frequent (80-99%)HP:0010615

Enlarged parathyroid glands

Very frequent (80-99%)HP:0008208

Hypercalcemia

Very frequent (80-99%)HP:0003072

Impairment of activities of daily living

Very frequent (80-99%)HP:0031058

Primary hyperparathyroidism

Very frequent (80-99%)HP:0008200

Adrenocortical abnormality

Frequent (30-79%)HP:0000849

Cancer of the pancreas

Frequent (30-79%)HP:0002894

Decreased bone mineral density Z score

Frequent (30-79%)HP:0004349

Decreased male libido

Frequent (30-79%)HP:0040306

Diarrhea

Frequent (30-79%)HP:0002014

Difficulty getting an erection

Frequent (30-79%)HP:0000802

Galactorrhea

Frequent (30-79%)HP:0100829

Gastro-esophageal reflux

Frequent (30-79%)HP:0002020

Hypercalciuria

Frequent (30-79%)HP:0002150

Increased blood gastrin

Frequent (30-79%)HP:0500167

Large cafe-au-lait macules with irregular margins

Frequent (30-79%)HP:0005605

Multiple lipomas

Frequent (30-79%)HP:0001012

Pituitary adenoma

Frequent (30-79%)HP:0002893

Prolactinoma

Frequent (30-79%)HP:0006767

Sore in the lining of gastrointestinal tract

Frequent (30-79%)HP:0004398

Stomach pain

Frequent (30-79%)HP:0002027

Weight loss

Frequent (30-79%)HP:0001824

Zollinger-Ellison syndrome

Frequent (30-79%)HP:0002044

Abnormal plasma aldosterone

Occasional (5-29%)HP:0040085

ACTH-independent hypercortisolemia

Occasional (5-29%)HP:0001579

Adrenocortical adenoma

Occasional (5-29%)HP:0008256

Adrenocortical carcinoma

Occasional (5-29%)HP:0006744

Amenorrhea

Occasional (5-29%)HP:0000141

Black faeces

Occasional (5-29%)HP:0002249

Breakdown of bone

Occasional (5-29%)HP:0002797

Related Conditions

Polyglandular activity in multiple endocrine adenomatosis(parent)

Genetic disease(parent)

Quick Facts

SNOMED CT: 30664006
UMLS CUI: C0025267
Fully Specified Name: Multiple endocrine neoplasia, type 1 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.