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Proximal 11p deletion syndrome

disorder
SNOMED 702346005CUI C1832588

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Multiple exostoses
Always present (100%)HP:0002762
Broad, upturned nose
Very frequent (80-99%)HP:0000455
Convex bridge of nose
Very frequent (80-99%)HP:0000426
Decreased mineralization of skull
Very frequent (80-99%)HP:0004331
Decreased projection of lower jaw
Very frequent (80-99%)HP:0000347
Formation of new noncancerous bone on top of existing bone
Very frequent (80-99%)HP:0100777
Mental and motor retardation
Very frequent (80-99%)HP:0001263
Nasal tip, depressed
Very frequent (80-99%)HP:0000437
Palpebronasal fold
Very frequent (80-99%)HP:0000286
Single flexion crease
Very frequent (80-99%)HP:0000954
Small nasal alae
Very frequent (80-99%)HP:0000430
Wide skull shape
Very frequent (80-99%)HP:0000248
Brachydactyly
Frequent (30-79%)HP:0001156
Central hypotonia
Frequent (30-79%)HP:0001252
Craniofacial dysostosis
Frequent (30-79%)HP:0004439
Decreased height of philtrum
Frequent (30-79%)HP:0000322
Downturned corners of mouth
Frequent (30-79%)HP:0002714
Extra bones within cranial sutures
Frequent (30-79%)HP:0002645
Increased intercanthal distance
Frequent (30-79%)HP:0000506
Involuntary, rapid, rhythmic eye movements
Frequent (30-79%)HP:0000639
Laterally sparse eyebrows
Frequent (30-79%)HP:0005338
Persistent foramina of the parietal bones
Frequent (30-79%)HP:0002697
Seizures
Frequent (30-79%)HP:0001250
Short penis
Frequent (30-79%)HP:0000054
Squint
Frequent (30-79%)HP:0000486
Cutaneous syndactyly between fingers 2 and 5
Occasional (5-29%)HP:0005650
Delayed puberty
Occasional (5-29%)HP:0000823
High blood pressure
Occasional (5-29%)HP:0000822
Hypothyroidism
Occasional (5-29%)HP:0000821
Low intelligence
Occasional (5-29%)HP:0001249

Quick Facts

SNOMED CT
702346005
UMLS CUI
C1832588
Fully Specified Name
Chromosome 11p11.2 deletion syndrome (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.