Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Factor VIII deficiency
Very frequent (80-99%)HP:0003125
Prolonged activated partial thromboplastin time
Very frequent (80-99%)HP:0003645
Bruising susceptibility
Frequent (30-79%)HP:0000978
Excessive bleeding after minor trauma
Frequent (30-79%)HP:0001934
Joint hemorrhage
Frequent (30-79%)HP:0005261
Joint swelling
Frequent (30-79%)HP:0001386
Nasal hemorrhage
Frequent (30-79%)HP:0000421
Oral cavity bleeding
Frequent (30-79%)HP:0030140
Poor wound healing
Frequent (30-79%)HP:0001058
Protracted bleeding after surgery
Frequent (30-79%)HP:0004846
Arthralgias
Occasional (5-29%)HP:0002829
Cephalohematoma
Occasional (5-29%)HP:0012541
Epidural hematoma
Occasional (5-29%)HP:0100310
Gastrointestinal haemorrhage
Occasional (5-29%)HP:0002239
Headache
Occasional (5-29%)HP:0002315
Hypermenorrhea
Occasional (5-29%)HP:0000132
Intracranial haemorrhage
Occasional (5-29%)HP:0002170
Intramuscular haematoma
Occasional (5-29%)HP:0012233
Limb joint contracture
Occasional (5-29%)HP:0003121
Limitation of joint mobility
Occasional (5-29%)HP:0001376
Low number of red blood cells or haemoglobin
Occasional (5-29%)HP:0001903
Macroscopic hematuria
Occasional (5-29%)HP:0012587
Progressive joint destruction
Occasional (5-29%)HP:0005187
Prolonged bleeding following circumcision
Occasional (5-29%)HP:0030137
Reduced von Willebrand factor activity
Occasional (5-29%)HP:0008330
Subdural haematoma
Occasional (5-29%)HP:0100309
Synovitis
Occasional (5-29%)HP:0100769
Related Conditions
Quick Facts
- SNOMED CT
- 16872008
- UMLS CUI
- C0272322
- Fully Specified Name
- Severe hereditary factor VIII deficiency disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 27
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.