Systemic mastocytosis with associated clonal haematological non-mast cell lineage disease

disorder

SNOMED 397015000CUI C1301365

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormality of mastocytes

Very frequent (80-99%)HP:0100494

Blood tumor

Very frequent (80-99%)HP:0004377

Elevated total serum tryptase

Very frequent (80-99%)HP:0031901

Myeloid leukaemia

Very frequent (80-99%)HP:0012324

Bone marrow hypercellularity

Frequent (30-79%)HP:0031020

Eosinophilia

Frequent (30-79%)HP:0001880

Headache

Frequent (30-79%)HP:0002315

Increased total leukocyte count

Frequent (30-79%)HP:0001974

Low platelet count

Frequent (30-79%)HP:0001873

Myeloproliferative disorder

Frequent (30-79%)HP:0005547

Normochromic anaemia

Frequent (30-79%)HP:0001895

Normocytic anemia

Frequent (30-79%)HP:0001897

Paleness

Frequent (30-79%)HP:0000980

Pyrexia

Frequent (30-79%)HP:0001945

Skin itching

Frequent (30-79%)HP:0000989

Tiredness

Frequent (30-79%)HP:0012378

Weight loss

Frequent (30-79%)HP:0001824

Abdominal discomfort

Occasional (5-29%)HP:0002027

Abnormality of the respiratory system

Occasional (5-29%)HP:0002086

Acute myeloid leukaemia

Occasional (5-29%)HP:0004808

Arthritic pain

Occasional (5-29%)HP:0002829

Bone pain

Occasional (5-29%)HP:0002653

Cancer of lymphatic system

Occasional (5-29%)HP:0002665

Chronic myelomonocytic leukemia

Occasional (5-29%)HP:0012325

Diarrhea

Occasional (5-29%)HP:0002014

Elevated heart rate

Occasional (5-29%)HP:0001649

Enlarged liver

Occasional (5-29%)HP:0002240

Flushing

Occasional (5-29%)HP:0031284

Granulocytic hyperplasia

Occasional (5-29%)HP:0012138

Hives

Occasional (5-29%)HP:0001025

Related Conditions

Neoplasm affecting hematopoietic structure(parent)

Malignant mastocytosis(parent)

Quick Facts

SNOMED CT: 397015000
UMLS CUI: C1301365
Fully Specified Name: Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.