Substance / Medication

Acetylcholine

Overview

Active Ingredient
acetylcholine
RxNorm CUI
194

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

No related conditions have been mapped yet. Condition-intervention linkages are derived from SNOMED CT relationships and will expand as the knowledge graph grows.

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
A Systematic Review on Drugs Acting as Nicotinic Acetylcholine Receptor Agonists in the Treatment of Dementia.
Crestini Alessio, Carbone Elena, Rivabene Roberto et al. · Cells · 2024
PMID: 38334629Meta-AnalysisFull text (PMC)
A systematic review of genetic variation within nicotinic acetylcholine receptor genes and cigarette smoking cessation.
Jones Stephanie K, Wolf Bethany J, Froeliger Brett et al. · Drug Alcohol Depend · 2022
PMID: 35981468Meta-AnalysisFull text (PMC)
Ineffectiveness of nicotinic acetylcholine receptor antagonists for treatment-resistant depression: a meta-analysis.
Wang Hee Ryung, Woo Young Sup, Bahk Won-Myong · Int Clin Psychopharmacol · 2016
PMID: 26982579Meta-Analysis
Neurobiological impact of nicotinic acetylcholine receptor agonists: an activation likelihood estimation meta-analysis of pharmacologic neuroimaging studies.
Sutherland Matthew T, Ray Kimberly L, Riedel Michael C et al. · Biol Psychiatry · 2015
PMID: 25662104Meta-AnalysisFull text (PMC)
Identifying genetic variants for heart rate variability in the acetylcholine pathway.
Riese Harriëtte, Muñoz Loretto M, Hartman Catharina A et al. · PLoS One · 2014
PMID: 25384021Meta-AnalysisFull text (PMC)
The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: a meta-analysis.
Noori Hamid R, Fliegel Sarah, Brand Ines et al. · Synapse · 2012
PMID: 22733599Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Acetylcholine (substance)
SNOMED CT
57308006
UMLS CUI
C0001041
RxNorm CUI
194

Clinical Data

This intervention maps to 0 entities in the Ltrl knowledge graph.

0
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.