Back to Interventions
Substance / Medication

Allantoin

SNOMED 395933009UMLS C0002083

Overview

Active Ingredient
allantoin
RxNorm CUI
508

Indications

Scartrate™ Cream is indicated for temporary protection and relief of chapped or cracked skin, it also effectively reduces the overall appearance of scars.

Labeler: Puretek CorporationUpdated: 2025-05-07T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Do not use on deep or puncture wounds, animal bites, or serious burns.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Congenital anomaly of skin

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Recent Trials

Effects of Treatments on Atopic Dermatitis

NCT01631617Phase 2Recruiting130 enrolled
View all 1 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and Safety of Topical Compound Heparin Sodium Allantoin Gel (Main Components: Onion Extract Quercetin) for the Treatment of Rosacea.
Xu Zining, Yu Biao, Qing Yuxin et al. · J Cosmet Dermatol · 2025
PMID: 40177799RCTFull text (PMC)
A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo.
Leeyaphan Charussri, Varothai Supenya, Trakanwittayarak Suphattra et al. · J Cosmet Dermatol · 2022
PMID: 33811776RCT
Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial.
Sáez-Alcaide L-M, Molinero-Mourelle P, González-Serrano J et al. · Med Oral Patol Oral Cir Bucal · 2020
PMID: 32683390RCTFull text (PMC)
Effectiveness and Safety of an Overnight Patch Containing Allium cepa Extract and Allantoin for Post-Dermatologic Surgery Scars.
Prager Welf, Gauglitz Gerd G · Aesthetic Plast Surg · 2018
PMID: 29948103RCTFull text (PMC)
The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction.
Madrazo-Jiménez M, Rodríguez-Caballero Á, Serrera-Figallo M-Á et al. · Med Oral Patol Oral Cir Bucal · 2016
PMID: 27475700RCTFull text (PMC)
The prophylactic use of a topical scar gel containing extract of Allium cepae, allantoin, and heparin improves symptoms and appearance of cesarean-section scars compared with untreated scars.
Ocampo-Candiani Jorge, Vázquez-Martínez Osvaldo T, Iglesias Benavides José Luis et al. · J Drugs Dermatol · 2014
PMID: 24509969RCT
A double-blind randomised controlled trial of a natural oil-based emulsion (Moogoo Udder Cream®) containing allantoin versus aqueous cream for managing radiation-induced skin reactions in patients with cancer.
Chan Raymond Javan, Keller Jacqui, Cheuk Robyn et al. · Radiat Oncol · 2012
PMID: 22849762RCTFull text (PMC)
Effect of allium cepa-allantoin-pentaglycan gel on skin hypertrophic scars: clinical and video-capillaroscopic results of an open-label, controlled, nonrandomized clinical trial.
Campanati Anna, Savelli Andrea, Sandroni Lucia et al. · Dermatol Surg · 2010
PMID: 20626444RCT
Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.
Ho Wai Sun, Ying Shun Yuen, Chan Pik Chu et al. · Dermatol Surg · 2006
PMID: 16875470RCT
Rapid and reliable HILIC-MS/MS method for monitoring allantoin as a biomarker of oxidative stress.
Kozlik Petr, Hasikova Lenka, Stiburkova Blanka et al. · Anal Biochem · 2020
PMID: 31747555Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Allantoin (substance)
SNOMED CT
395933009
UMLS CUI
C0002083
RxNorm CUI
508
Labeler
Puretek Corporation

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.