Substance / Medication

Amphetamine sulfate

SNOMED 87148003 UMLS C0282051

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Narcolepsy

Attention deficit hyperactivity disorder

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

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The effects of L-amphetamine sulfate on cognition in MS patients: results of a randomized controlled trial.

Morrow Sarah A, Kaushik Tanya, Zarevics Peter et al. · J Neurol · 2009

PMID: 19263186RCT

Effects of l-amphetamine sulfate on cognitive function in multiple sclerosis patients.

Benedict R H B, Munschauer F, Zarevics P et al. · J Neurol · 2008

PMID: 18481035RCT

A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of AR19, a Manipulation-Resistant Formulation of Amphetamine Sulfate, in Adults With Attention-Deficit/Hyperactivity Disorder.

Faraone Stephen V, Childress Ann, Caras Steve et al. · J Clin Psychiatry · 2021

PMID: 34428356Observational

Pharmacokinetics of AR19, an Immediate-Release Amphetamine Sulfate Formulation Designed to Deter Manipulation for Administration Via Nonoral Routes: Bioequivalence to Reference Racemic Amphetamine Sulfate, Dose Proportionality, and Food Effect.

Caras Steven, Sharpe Terrilyn · J Child Adolesc Psychopharmacol · 2020

PMID: 31809216Observational

Gender Effects in the Efficacy of Racemic Amphetamine Sulfate in Children with Attention-Deficit/Hyperactivity Disorder.

Childress Ann C, Newcorn Jeffrey H, Cutler Andrew J · Adv Ther · 2019

PMID: 30972657ObservationalFull text (PMC)

The Efficacy and Safety of Evekeo, Racemic Amphetamine Sulfate, for Treatment of Attention-Deficit/Hyperactivity Disorder Symptoms: A Multicenter, Dose-Optimized, Double-Blind, Randomized, Placebo-Controlled Crossover Laboratory Classroom Study.

Childress Ann C, Brams Matthew, Cutler Andrew J et al. · J Child Adolesc Psychopharmacol · 2015

PMID: 25692608ObservationalFull text (PMC)

Assessment of silver and gold substrates for the detection of amphetamine sulfate by surface enhanced Raman scattering (SERS).

Faulds K, Smith W E, Graham D et al. · Analyst · 2002

PMID: 11913874Observational

Dextroamphetamine sulfate provided quick relief of severe post-partum depression that was recalcitrant to standard antidepressants and psychotherapy.

Check J H, Jaffe A · Clin Exp Obstet Gynecol · 2017

PMID: 29746037Case Report

Dextroamphetamine sulfate treatment eradicates long-term chronic severe headaches from temporomandibular joint syndrome--a case that emphasizes the role of the gynecologist in treating headaches in women.

Check J H · Clin Exp Obstet Gynecol · 2016

PMID: 27048031Case Report

Complete resolution of frozen shoulder syndrome in a woman treated with dextroamphetamine sulfate for chronic urinary urgency.

Check J H, Cohen R · Clin Exp Obstet Gynecol · 2015

PMID: 26524823Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Amfetamine sulfate (substance)
SNOMED CT: 87148003
UMLS CUI: C0282051

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.