Substance / Medication

Bethanechol

Overview

Active Ingredient
bethanechol
RxNorm CUI
19257

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
1
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis.
Moral Nakamura Denise, da Graça Pinto Henrique, Baena Elchin Cintia et al. · Radiother Oncol · 2023
PMID: 37207874Meta-Analysis
Bethanechol used to prevent salivary gland dysfunction in patients submitted to radioactive iodine therapy: A double blind, placebo-controlled, randomized study.
Campanhã Daniel, PereiraLIMA Eduardo Nóbrega, Alves Fábio Abreu et al. · J Stomatol Oral Maxillofac Surg · 2022
PMID: 34954424RCT
Release-modulating mechanism and comparative pharmacokinetics in beagle dogs of bethanechol-loaded oral dosage forms.
Jeong Hyeong-Mo, Kim Hansol, Jang Taeyeon et al. · Int J Pharm · 2025
PMID: 39701474Observational
Postoperative analgesia induced by intrathecal neostigmine or bethanechol in rats.
Prado W A, Dias T B · Clin Exp Pharmacol Physiol · 2009
PMID: 19076163Observational
The effects of bethanechol and cisapride on urodynamic parameters in patients undergoing radical hysterectomy for cervical cancer. A randomized, double-blind, placebo-controlled study.
Madeiro Alberto P, Rufino Andréa C, Sartori Marair G F et al. · Int Urogynecol J Pelvic Floor Dysfunct · 2006
PMID: 15959612Observational
M3 muscarinic receptor-deficient mice retain bethanechol-mediated intestinal ion transport and are more sensitive to colitis.
Hirota Christina L, McKay Derek M · Can J Physiol Pharmacol · 2006
PMID: 17218980Observational
Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats.
Prado Wiliam A, Segalla Daniel K · Brain Res · 2004
PMID: 15276888Observational
Bethanechol as a Corrective for Urinary Retention Associated With Olanzapine Administration.
Greco Frank A, Simms Nicholas J, Athappilly Geena K · Prim Care Companion CNS Disord · 2019
PMID: 31682336Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Bethanechol (substance)
SNOMED CT
372698003
UMLS CUI
C0053526
RxNorm CUI
19257

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.