Substance / Medication

Buprenorphine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.
Xie Xiaohu, Gu Jun, Zhuang Dingding et al. · J Clin Lab Anal · 2022
PMID: 36305091Meta-AnalysisFull text (PMC)
Effectiveness of psychosocial interventions for reducing parental substance misuse.
McGovern Ruth, Newham James J, Addison Michelle T et al. · Cochrane Database Syst Rev · 2021
PMID: 33723860Meta-AnalysisFull text (PMC)
Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence.
McCorkle Maggie L, Kisor David F, Freiermuth Caroline E et al. · Pharmacogenomics · 2021
PMID: 34424051Meta-Analysis
Prevalence of respiratory conditions among people who use illicit opioids: a systematic review.
Hulin Joe, Brodie Arjuna, Stevens John et al. · Addiction · 2020
PMID: 31692109Meta-Analysis
Cocaine dependence: "Side effects" and syndrome formation within 1-12 months after first cocaine use.
Chandra Madhur, Anthony James C · Drug Alcohol Depend · 2020
PMID: 31753734Meta-Analysis
Effects of stimulant drug use on the dopaminergic system: A systematic review and meta-analysis of in vivo neuroimaging studies.
Proebstl Lisa, Kamp Felicia, Manz Kirsi et al. · Eur Psychiatry · 2019
PMID: 30981746Meta-Analysis
Evaluation of thermal antinociceptive effects after intramuscular administration of buprenorphine hydrochloride to American kestrels (Falco sparverius).
Ceulemans Susanne M, Guzman David Sanchez-Migallon, Olsen Glenn H et al. · Am J Vet Res · 2014
PMID: 25061700RCT
Postcastration analgesia in ponies using buprenorphine hydrochloride.
Love E J, Taylor P M, Whay H R et al. · Vet Rec · 2013
PMID: 23736517RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Buprenorphine hydrochloride (substance)
SNOMED CT
21066009
UMLS CUI
C0701445

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.