No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

13 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Recurrent Throat Infections and Tonsillectomy

NCT00547391Phase 4Completed87 enrolled

Multicenter, Open, Randomized Comparative Trial To Compare The Efficacy Of Azithromycin Versus Amoxicillin In Children With Strep Throat

NCT00643539Phase 4Completed360 enrolled

Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy

NCT00654511Phase 4Completed101 enrolled

Efficacy of Tinoridine in Treating Pain and Inflammation in Adults

NCT01224756Phase 4Completed342 enrolled

A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy

NCT01267136Phase 4Completed84 enrolled

View all 13 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

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A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects.

Hernández-Mitre María Patricia, Wallis Steven C, Morgan Elizabeth E et al. · Antimicrob Agents Chemother · 2024

PMID: 38059635RCTFull text (PMC)

Pharmacokinetics and safety of single and repeat doses of ceftibuten in healthy participants: a phase 1 dose escalation study.

Dorr Mary Beth, de Oliveira Carlos Fernando, van de Wetering Jeroen et al. · Antimicrob Agents Chemother · 2025

PMID: 40762485TrialFull text (PMC)

Safety and pharmacokinetics of single and multiple doses of ledaborbactam etzadroxil with or without ceftibuten in healthy volunteers.

de Oliveira Carlos Fernando, Dorr Mary Beth, van de Wetering Jeroen et al. · Antimicrob Agents Chemother · 2025

PMID: 40762486TrialFull text (PMC)

Fewer bacterial relapses after oral treatment with norfloxacin than with ceftibuten in acute pyelonephritis initially treated with intravenous cefuroxime.

Cronberg S, Banke S, Bergman B et al. · Scand J Infect Dis · 2001

PMID: 11440218Trial

[Patient adherence in respiratory tract infections: ceftibuten versus other antibiotics (PARTICULAR study)].

Kardas P, Ratajczyk-Pakalska E · Pol Merkur Lekarski · 2001

PMID: 11503260Trial

Oral ceftibuten switch therapy for acute pyelonephritis in children.

Vilaichone A, Watana D, Chaiwatanarat T · J Med Assoc Thai · 2001

PMID: 11529382Trial

Comparative study of ceftibuten and cefixime in the treatment of complicated urinary tract infections.

Ho M W, Wang F D, Fung C P et al. · J Microbiol Immunol Infect · 2001

PMID: 11605809Trial

[Five days ceftibuten versus 10 days penicillin in the treatment of 2099 patients with A-streptococcal tonsillopharyngitis].

Adam D, Scholz H, Helmerking M · Fortschr Med Orig · 2001

PMID: 15704358Trial

Ceftibuten in enteric fever.

Dubey A K, Vidyashankar C, Bhatia S S et al. · Indian Pediatr · 2000

PMID: 10745426Trial

Efficacy of ceftibuten in 5 versus 10 days treatment of recurrent acute otitis media in children.

Roos K, Larsson P · Int J Pediatr Otorhinolaryngol · 2000

PMID: 11006450Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Ceftibuten (substance)
SNOMED CT: 387535008
UMLS CUI: C0055014
RxNorm CUI: 20492

Clinical Data

This intervention maps to 8 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.