Substance / Medication

Ciprofloxacin

Overview

Active Ingredient
ciprofloxacin
RxNorm CUI
2551
Labeler: ProPharma DistributionUpdated: 2025-11-04T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Fluoroquinolones, including Ciprofloxacin Injection (in 5% Dextrose Injection), have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together 5.1 [see Warnings and Precautions ()] including: Discontinue Ciprofloxacin Injection (in 5% Dextrose

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

46 trials linked to this intervention

46
Total Trials
7
Recruiting
6
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Ciprofloxacin resistance in community and hospital-acquired urinary tract infections: a systematic review and meta-analysis from African population.
Kibwana Upendo O, Manyahi Joel, Sabas Deodatus M et al. · BMC Infect Dis · 2025
PMID: 41455903Meta-Analysis
Prophylactic fluoroquinolones in hematopoietic stem cell transplant recipients: A meta-analytic comparison of ciprofloxacin and levofloxacin.
Albalawi Mohammed A Hameed, Al-Sayaghi Khaled Mohammed, Hegazy Samya Mohamed et al. · Medicine (Baltimore) · 2025
PMID: 40355203Meta-AnalysisFull text (PMC)
Ciprofloxacin-induced cutaneous adverse drug events: a systematic review of descriptive studies.
Kashyap Ananth, Sreenivasan Sahana, Rajan Asha K et al. · J Basic Clin Physiol Pharmacol · 2021
PMID: 33725760Meta-Analysis
Meta-analysis of efficacy and safety of inhaled ciprofloxacin in non-cystic fibrosis bronchiectasis patients.
Wang Sumei, Zhang Aiping, Yao Xin · Intern Med J · 2021
PMID: 33469994Meta-Analysis
A systematic review and meta-analysis of levofloxacin and ciprofloxacin in the treatment of urinary tract infection.
Xue Zhisong, Xiang Ying, Li Yutao et al. · Ann Palliat Med · 2021
PMID: 34628902Meta-Analysis
Quantifying the contribution of four resistance mechanisms to ciprofloxacin MIC in Escherichia coli: a systematic review.
van der Putten Boas C L, Remondini Daniel, Pasquini Giovanni et al. · J Antimicrob Chemother · 2019
PMID: 30357339Meta-Analysis
Ciprofloxacin use in neonates: a systematic review of the literature.
Kaguelidou Florentia, Turner Mark A, Choonara Imti et al. · Pediatr Infect Dis J · 2011
PMID: 21048525Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Ciprofloxacin (substance)
SNOMED CT
372840008
UMLS CUI
C0008809
RxNorm CUI
2551
Labeler
ProPharma Distribution

Clinical Data

This intervention maps to 25 entities in the Healos knowledge graph.

20
Conditions
2
Biomarkers
2
Specialists
0
Symptoms
46
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Ciprofloxacin — Conditions, Biomarkers & Specialists | Healos | Ltrl