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Substance / Medication

Citrate

SNOMED 59351004 UMLS C0376259

Overview

Active Ingredient

citrate

RxNorm CUI

114200

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

LOINC 10567-6

name_match

Clinical Trials

7 trials linked to this intervention

7

Total Trials

2

Recruiting

0

With Results

Recent Trials

Arterial pH and Total Body Nitrogen Balances in APD

NCT00586131Phase 4Completed8 enrolled

Alkalinization by Urologists & Nephrologists

NCT03035812Phase 4Completed156 enrolled

Preserve-Transplant Study

NCT03102996Phase 4Completed240 enrolled

Optimal Dosage of Acetazolamide for OSA Treatment

NCT04726982Phase 4Completed91 enrolled

Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

NCT05005793Phase 4Recruiting120 enrolled

View all 7 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Clomiphene or enclomiphene citrate for the treatment of male hypogonadism: a systematic review and meta-analysis of randomized controlled trials.

Hohl Alexandre, Chavez Matheus Pedrotti, Pasqualotto Eric et al. · Arch Endocrinol Metab · 2025

PMID: 41066380Meta-AnalysisFull text (PMC)

Lactate as a Predictor of Citrate Accumulation in Patients Undergoing Continuous Renal Replacement Therapy? A Systematic Review.

Ulrichsen Johan U, Plovsing Ronni R, Foss Nicolai B et al. · Acta Anaesthesiol Scand · 2025

PMID: 40387608Meta-Analysis

Regional Citrate vs. Systemic Unfractionated Heparin Anticoagulation for Continuous Renal Replacement Therapy in Paediatric Patients: Systematic Review and Meta-Analysis.

Wang Yi, Yang Lan, Liu Yaping et al. · Nephrology (Carlton) · 2025

PMID: 40785699Meta-Analysis

Safety and efficacy of ivosidenib in the treatment of isocitrate dehydrogenase 1 mutant cholangiocarcinoma and acute myeloid leukemia: a systematic review and meta-analysis.

Qasim Rameez, Anmol Laraib, Shakeel Izza et al. · Anticancer Drugs · 2025

PMID: 40699201Meta-Analysis

Combined Letrozole and Clomiphene Citrate Versus Letrozole Alone in Ovulation Induction for Polycystic Ovarian Syndrome Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Alhebshi Zainah Abdulbari, Alqarni Dalia Hamed, Najjar Albaraa A et al. · Reprod Sci · 2025

PMID: 41120691Meta-Analysis

Citrate as a safe and effective alternative to heparin for catheter locking: a systematic review and meta-analysis of randomized controlled trials.

Lai Binbin, Huang Weixing, Yu Hui et al. · Front Med (Lausanne) · 2025

PMID: 40078385Meta-AnalysisFull text (PMC)

Diluted Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy in Pediatric Patients: A Systematic Review and Suggested Practice Points.

Sethi Sidharth Kumar, Tolwani Ashita, Ashruf Omer S et al. · Blood Purif · 2025

PMID: 40258350Meta-Analysis

Regional Citrate Anticoagulation Versus Systemic Heparin in Continuous Kidney Replacement Therapy: Examining the Role of Evidence in Health Technology Assessment.

Rognoni Carla, Pohlmeier Robert, Tarricone Rosanna · Adv Ther · 2025

PMID: 40238058Meta-AnalysisFull text (PMC)

Efficient administration of a combination of nifedipine and sildenafil citrate versus only nifedipine on clinical outcomes in women with threatened preterm labor: a systematic review and meta-analysis.

Manouchehri Elham, Makvandi Somayeh, Razi Mahdieh et al. · BMC Pediatr · 2024

PMID: 38341578Meta-AnalysisFull text (PMC)

Comparison of Letrozole and Clomiphene Citrate in Pregnancy Outcomes in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.

Abu-Zaid Ahmed, Gari Abdulrahim, Sabban Hussein et al. · Reprod Sci · 2024

PMID: 38030814Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Citrate (substance)
SNOMED CT: 59351004
UMLS CUI: C0376259
RxNorm CUI: 114200

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

1

Conditions

1

Biomarkers

0

Specialists

0

Symptoms

7

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.