Substance / Medication

Coagulation factor VII

Overview

Active Ingredient
factor VII
RxNorm CUI
4254

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
[Role of small-dose recombinant human coagulation factor VIIa for coagulopathy in patients with isolated traumatic brain injury].
Pei Bing-bing, Li Chao-yue, Lu Xin et al. · Zhonghua Yi Xue Za Zhi · 2013
PMID: 24124708RCT
Safety and pharmacokinetics of a recombinant fusion protein linking coagulation factor VIIa with albumin in healthy volunteers.
Golor G, Bensen-Kennedy D, Haffner S et al. · J Thromb Haemost · 2013
PMID: 24112951RCT
A limited sampling strategy for estimating individual pharmacokinetic parameters of coagulation factor VIII in patients with hemophilia A.
Bolon-Larger Magali, Chamouard Valérie, Bressolle Françoise et al. · Ther Drug Monit · 2007
PMID: 17304146RCT
Influence of Coagulation Factor VIII on Ischemic Stroke.
Martínez-Salmerón María Del Mar, Amaya-Pascasio Laura, Martínez-Sánchez Patricia et al. · Rev Neurol · 2026
PMID: 41609132Observational
Comparison between coagulation factor VIII quantified with one-stage activity assay and with mass spectrometry in haemophilia A patients: Proof of principle.
Donners Anouk A M T, van Maarseveen Erik M, Weetink Yrea R J et al. · Int J Lab Hematol · 2020
PMID: 32633067ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Coagulation factor VII (substance)
SNOMED CT
30804005
UMLS CUI
C0015502
RxNorm CUI
4254

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.