Substance / Medication

Cobalt

Overview

Active Ingredient
cobalt
RxNorm CUI
1310300

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Metal-on-metal arthroplasty, cobalt toxicity, and development of cognitive impairment: a systematic review.
Beshr Mostafa, Myint Phyo Kyaw, Rankin Iain et al. · Arch Orthop Trauma Surg · 2025
PMID: 40244464Meta-Analysis
Performance of polyetheretherketone (PEEK) versus cobalt chromium to fabricate removable partial denture frameworks: A systematic review.
Srivastava Gunjan, Padhiary Subrat Kumar, Schimmel Martin et al. · J Prosthet Dent · 2025
PMID: 40555611Meta-Analysis
Effect of sanitizing solutions on cobalt chromium alloys for dental prostheses: A systematic review of in vitro studies.
Timbó Isabelle C G, Oliveira Mayara S C S, Regis Rômulo R · J Prosthet Dent · 2024
PMID: 36357193Meta-Analysis
Accurate analysis of titanium and PolyEtherEtherKetone materials as an alternative to cobalt-chrome framework in removable partial denture: A systematic review.
Bertotti Karine, Mwenge-Wambel Julia, Sireix Christophe et al. · Dent Mater · 2024
PMID: 39191558Meta-Analysis
Efficacy of Nanoparticles in dose enhancement with high dose rate of Iridium-192 and Cobalt-60 radionuclide sources in the Treatment of Cancer: A systematic review.
Gebremariam Tsige Y, Geraily Ghazale, Arero Amanuel G et al. · J Cancer Res Ther · 2023
PMID: 38384008Meta-Analysis
Ceramic Femoral Heads Exhibit Lower Wear Rates Compared to Cobalt Chrome: A Meta-Analysis.
Mertz Kevin C, Yang JaeWon, Chung Brian C et al. · J Arthroplasty · 2023
PMID: 36108994Meta-Analysis
Site-specific cancer risk following cobalt exposure via orthopedic implants or in occupational settings: A systematic review and meta-analysis.
Holy Chantal E, Zhang Shumin, Perkins Laura E et al. · Regul Toxicol Pharmacol · 2022
PMID: 34896478Meta-Analysis
Adhesion of veneering porcelain to cobalt-chromium dental alloys processed with casting, milling, and additive manufacturing methods: A systematic review and meta-analysis.
Revilla-León Marta, Gómez-Polo Miguel, Park So Hyeon et al. · J Prosthet Dent · 2022
PMID: 34294418Meta-Analysis
Carcinogenic hazard assessment of cobalt-containing alloys in medical devices: Review of in vivo studies.
Kovochich Michael, Monnot Andrew, Kougias Daniel G et al. · Regul Toxicol Pharmacol · 2021
PMID: 33662479Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cobalt (substance)
SNOMED CT
54808007
UMLS CUI
C0009148
RxNorm CUI
1310300

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

1
Conditions
1
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.