Substance / Medication

Cyclobenzaprine

Overview

Active Ingredient
cyclobenzaprine
RxNorm CUI
21949

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Cyclobenzaprine for the treatment of myofascial pain in adults.
Leite Frederico M G, Atallah Alvaro N, El Dib Regina et al. · Cochrane Database Syst Rev · 2009
PMID: 19588406Meta-AnalysisFull text (PMC)
Treatment of fibromyalgia with cyclobenzaprine: A meta-analysis.
Tofferi Jeanne K, Jackson Jeffrey L, O'Malley Patrick G · Arthritis Rheum · 2004
PMID: 14872449Meta-Analysis
Cyclobenzaprine and back pain: a meta-analysis.
Browning R, Jackson J L, O'Malley P G · Arch Intern Med · 2001
PMID: 11434793Meta-Analysis
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
Friedman Benjamin W, Dym Andrew A, Davitt Michelle et al. · JAMA · 2015
PMID: 26501533RCT
Pharmacokinetics and bioequivalence evaluation of cyclobenzaprine tablets.
Brioschi Tatiane Maria de Lima Souza, Schramm Simone Grigoleto, Kano Eunice Kazue et al. · Biomed Res Int · 2013
PMID: 24151591RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cyclobenzaprine (substance)
SNOMED CT
373779004
UMLS CUI
C0056732
RxNorm CUI
21949

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.