Substance / Medication

Dantrolene

Overview

Active Ingredient
dantrolene
RxNorm CUI
3105

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Succinylcholine Use and Dantrolene Availability for Malignant Hyperthermia Treatment: Database Analyses and Systematic Review.
Larach Marilyn Green, Klumpner Thomas T, Brandom Barbara W et al. · Anesthesiology · 2019
PMID: 30550426Meta-Analysis
Dantrolene in the treatment of MDMA-related hyperpyrexia: a systematic review.
Grunau Brian E, Wiens Matthew O, Brubacher Jeffrey R · CJEM · 2010
PMID: 20880437Meta-Analysis
Dantrolene versus amiodarone for cardiopulmonary resuscitation: a randomized, double-blinded experimental study.
Wiesmann Thomas, Freitag Dennik, Dersch Wolfgang et al. · Sci Rep · 2017
PMID: 28098197RCTFull text (PMC)
Effect of dantrolene premedication on various cardiovascular and biochemical variables and the recovery in healthy isoflurane-anesthetized horses.
McKenzie Erica C, Di Concetto Stefano, Payton Mark E et al. · Am J Vet Res · 2015
PMID: 25815570RCT
Dantrolene for cerebral vasospasm after subarachnoid haemorrhage: a randomised double blind placebo-controlled safety trial.
Muehlschlegel Susanne, Carandang Raphael, Hall Wiley et al. · J Neurol Neurosurg Psychiatry · 2015
PMID: 25344064RCT
The inhibition of acetylcholinesterase by dantrolene and ondansetron.
N'Da C I, Petzer A, Petzer J P · Drug Res (Stuttg) · 2015
PMID: 24764253Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Dantrolene (substance)
SNOMED CT
372819007
UMLS CUI
C0010976
RxNorm CUI
3105

Clinical Data

This intervention maps to 11 entities in the Healos knowledge graph.

6
Conditions
3
Biomarkers
1
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Dantrolene — Conditions, Biomarkers & Specialists | Healos | Ltrl