No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

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Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials.

Wen Yulong, Tang Yidan, Li Miaoyue et al. · Pharm Biol · 2021

PMID: 34517748Meta-AnalysisFull text (PMC)

[Meta-analysis of efficacy and safety of Tripterygium Glycosides Tablets combined with desloratadine in treatment of chronic urticarial].

Shi Yan-Shuo, Wang Qi-Min, Qiu Xue-Jia et al. · Zhongguo Zhong Yao Za Zhi · 2019

PMID: 31602921Meta-Analysis

Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials.

Canonica G W, Tarantini F, Compalati E et al. · Allergy · 2007

PMID: 17362245Meta-Analysis

Efficacy and safety of combined oral isotretinoin and desloratadine vs. isotretinoin alone in acne vulgaris: a comparative study.

El-Ghareeb Mohamed Ibrahim, Kandeel Abdullah Hassan, Khayrullah Naeima Mohammed · Arch Dermatol Res · 2025

PMID: 40204949RCT

Comparative Efficacy of Mometasone Nasal Spray Combined with Different Doses of Desloratadine, and Montelukast in Childhood Allergic Rhinitis: A Randomized Clinical Trial.

Ghanbari Niloufar, Eftekhari Kambiz, Samadzadeh-Mamaghani Mohammadreza et al. · Iran J Allergy Asthma Immunol · 2024

PMID: 39549290RCT

Oral isotretinoin with desloratadine compared with oral isotretinoin alone in the treatment of moderate to severe acne: a randomized, assessor-blinded study.

Hazarika Neirita, Yadav Piyush, Bagri Manmohan et al. · Int J Dermatol · 2024

PMID: 38546101RCT

Comparison of aprepitant versus desloratadine for EGFR-TKI-induced pruritus: A randomized phase 2 clinical trial.

Zhou Ting, Zhang Yaxiong, Ma Yuxiang et al. · Cancer · 2022

PMID: 36197287RCT

Desloratadine citrate combined with compound glycyrrhizin in the treatment of subacute eczema: A randomized trial.

Wang Gang, Ye Aihua, Xu Xiangyu et al. · Pak J Pharm Sci · 2022

PMID: 35791588RCT

Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria.

Li Juan, Chen Wangqing, Peng Cong et al. · Pharmacogenomics J · 2020

PMID: 31406237RCT

A Randomized Study on the Bioequivalence of Desloratadine in Healthy Chinese Subjects and the Association of Different Metabolic Phenotypes With UGT2B10 and CYP2C8 Genotypes.

Niu Suping, Li Yan, Dong Wenliang et al. · Curr Drug Metab · 2020

PMID: 33109037RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Desloratadine (substance)
SNOMED CT: 396015008
UMLS CUI: C0908935
RxNorm CUI: 275635
Labeler: Lupin Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.