Substance / Medication

Dexamethasone

Overview

Active Ingredient
dexamethasone
RxNorm CUI
3264

Indications

Allergic States Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, and serum sickness. Dermatologic Diseases Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, and severe erythema multiforme (Stevens-Johnson syndrome). Endocrine Disorders Primary or secondary adrenocortical

Labeler: NuCare Pharmaceuticals, Inc.Updated: 2026-02-10T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

WARNINGS Systemic fungal infections (see, Fungal Infections). Dexamethasone tablets are contraindicated in patients who are hypersensitive to any components of this product.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

182 trials linked to this intervention

182
Total Trials
45
Recruiting
45
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Impact of dexamethasone-enhanced anaesthetics on postoperative pain, oedema, and trismus following third molar extraction: a systematic review and meta-analysis.
Fernandes I A, Protásio A C R, D'Angelis I et al. · Int J Oral Maxillofac Surg · 2026
PMID: 40849280Meta-Analysis
Effectiveness of Adding Dexamethasone to Lidocaine in Upper Limbs Nerve Blocks: A Systematic Review.
Rafiei Mohammad-Reza, Khani Ali Karbalai, Kheradmand Behroz et al. · J Perianesth Nurs · 2025
PMID: 39023476Meta-Analysis
Evaluating the Use of Dexamethasone in Diabetic Patients Undergoing Total Joint Arthroplasty: A Systematic Review and Meta-analysis.
Razick Daniel, Akhtar Muzammil, Ansari Ubaid et al. · J Arthroplasty · 2025
PMID: 39706354Meta-Analysis
DEXAMETHASONE INTRAVITREAL INJECTION IN DIABETIC PATIENTS UNDERGOING CATARACT SURGERY: An Updated Literature Review.
Meduri Alessandro, De Luca Laura, Oliverio Giovanni William et al. · Retina · 2025
PMID: 39787414Meta-Analysis
The dexamethasone suppression test as a biomarker for suicidal behavior: A systematic review and meta-analysis.
Spaan Pascalle, Verrijp Tessa, Michielsen Philip J S et al. · J Affect Disord · 2025
PMID: 39265870Meta-Analysis
Effects of dexamethasone on opioid consumption in pediatric tonsillectomy: a systematic review with meta-analysis.
Niimi Naoko, Sumie Makoto, Englesakis Marina et al. · Can J Anaesth · 2025
PMID: 39192047Meta-Analysis
Effects of combined dexamethasone and dexmedetomidine as adjuncts to peripheral nerve blocks: a systematic review with meta-analysis and trial sequential analysis.
Maagaard Mathias, Andersen Jakob Hessel, Jaeger Pia et al. · Reg Anesth Pain Med · 2025
PMID: 38253609Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Dexamethasone (substance)
SNOMED CT
372584003
UMLS CUI
C0011777
RxNorm CUI
3264
Labeler
NuCare Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 25 entities in the Healos knowledge graph.

20
Conditions
2
Biomarkers
2
Specialists
0
Symptoms
182
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.