Substance / Medication

Diphtheria antitoxin

Overview

Active Ingredient
diphtheria antitoxin
RxNorm CUI
3510

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
External quality assessment for the determination of diphtheria antitoxin in human serum.
Di Giovine Paolo, Pinto Antonella, Olander Rose-Marie et al. · Clin Vaccine Immunol · 2010
PMID: 20610661ObservationalFull text (PMC)
Standardization and validation of Vero cell assay for potency estimation of diphtheria antitoxin serum.
Kumar Sunil, Kanwar Sarika, Bansal Vivek et al. · Biologicals · 2009
PMID: 19540135Observational
European sero-epidemiology network: standardisation of the results of diphtheria antitoxin assays.
von Hunolstein C, Aggerbeck H, Andrews N et al. · Vaccine · 2000
PMID: 10869774Observational
Seroprevalence of IgG antibodies against diphtheria antitoxin among migrant workers in Singapore, 2016-2019.
Ang Li Wei, Gao Qi, Cui Lin et al. · BMC Public Health · 2022
PMID: 35033034Case ReportFull text (PMC)
Diphtheria antitoxin treatment: from pioneer to neglected.
Grandière Pérez Lucia, Brisse Sylvain · Mem Inst Oswaldo Cruz · 2025
PMID: 39841756ReviewFull text (PMC)
A Review of Adverse Events From the Use of Diphtheria Antitoxin (DAT) in the United States, 2004-2019.
Bampoe Valerie D, Boswell Haley C, Yu Yon C et al. · Clin Infect Dis · 2022
PMID: 34628502OtherFull text (PMC)
Diphtheria antitoxin potency assay: an in vitro alternative to the in vivo subcutaneous toxin neutralization test.
Bacellar Daniela Tendler Leibel, da Silva Cristiane Santino, Pereira-Júnior Antonio Alves et al. · Biologicals · 2026
PMID: 41386208Preclinical
Diphtheria Antitoxin Production and Procurement Practices and Challenges.
Marshall Caroline, Caro William Perea, Costa Alejandro et al. · Emerg Infect Dis · 2025
PMID: 41491021PreclinicalFull text (PMC)
Collaborative study for the calibration of a replacement International Standard for Diphtheria Antitoxin Equine.
Hassall Laura, Rigsby Peter, Stickings Paul · Biologicals · 2023
PMID: 37149975Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Diphtheria antitoxin (substance)
SNOMED CT
412175006
UMLS CUI
C0012547
RxNorm CUI
3510

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.