Substance / Medication

Doripenem

Overview

Active Ingredient
doripenem
RxNorm CUI
119771

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

6 trials linked to this intervention

6
Total Trials
0
Recruiting
4
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Meta-analysis of doripenem vs comparators in patients with pseudomonas infections enrolled in four phase III efficacy and safety clinical trials.
Jenkins Stephen G, Fisher Alan C, Peterson Janet A et al. · Curr Med Res Opin · 2009
PMID: 19849650Meta-Analysis
Comparative pharmacokinetics and pharmacodynamics of doripenem and meropenem in obese patients.
Kays Michael B, Fleming Megan R, Cheatham S Christian et al. · Ann Pharmacother · 2014
PMID: 24259653RCT
Pharmacodynamics of doripenem in critically ill patients with ventilator-associated Gram-negative bacilli pneumonia.
Jaruratanasirikul Sutep, Wongpoowarak Wibul, Kositpantawong Narongdet et al. · Int J Antimicrob Agents · 2012
PMID: 22959555RCT
Pharmacokinetics and monte carlo simulations of doripenem in patients with febrile neutropenia.
Stein Gary E, Kulhanek Grace, Smith Curtis L et al. · Ann Pharmacother · 2012
PMID: 23012385RCT
Pharmacokinetics of single-dose doripenem in adults with cystic fibrosis.
Cirillo Iolanda, Vaccaro Nicole, Redman Rebecca et al. · J Clin Pharmacol · 2012
PMID: 22174436RCT
Influence of continuous venovenous hemofiltration and continuous venovenous hemodiafiltration on the disposition of doripenem.
Cirillo Iolanda, Vaccaro Nicole, Balis Dainius et al. · Antimicrob Agents Chemother · 2011
PMID: 21199922RCTFull text (PMC)
In vitro Evaluation of Linezolid and Doripenem Clearance with Different Hemofilters.
Hiraiwa Toshihisa, Moriyama Kazuhiro, Matsumoto Kana et al. · Blood Purif · 2020
PMID: 31995801ObservationalFull text (PMC)
Doripenem versus meropenem as first-line empiric therapy of febrile neutropenia in patients with acute leukemia: a prospective, randomized study.
Oyake Tatsuo, Takemasa-Fujisawa Yuka, Sugawara Norifumi et al. · Ann Hematol · 2019
PMID: 30824955Observational
Doripenem dosing regimens in Asian critically ill patients with continuous renal replacement therapy.
Chaijamorn Weerachai, Puchsaka Punyawee, Pattharachayakul Sutthiporn et al. · J Crit Care · 2019
PMID: 31108327Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Doripenem (substance)
SNOMED CT
428352004
UMLS CUI
C0389169
RxNorm CUI
119771

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
6
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.