Substance / Medication

Edaravone

Overview

Active Ingredient
edaravone
RxNorm CUI
1921877

Indications

RADICAVA and RADICAVA ORS are indicated for the treatment of amyotrophic lateral sclerosis (ALS).

Labeler: Tanabe Pharma America, Inc.Updated: 2025-12-19T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

[see Warnings and Precautions (5.1 5.2 ,)]. RADICAVA and RADICAVA ORS are contraindicated in patients with a history of hypersensitivity to edaravone or any of the inactive ingredients in this product. Hypersensitivity reactions and anaphylactic reactions have occurred

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
1
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis.
Moghib Khaled, Hefnawy Mahmoud Tarek, Moawad Shehab M et al. · Front Neurol · 2025
PMID: 41111955Meta-AnalysisFull text (PMC)
Clinical efficacy of edaravone dexborneol in the treatment of acute ischemic stroke: meta-analysis.
Gao Haobo, Tan Hongtu, Wang Jiabin et al. · Front Neurol · 2025
PMID: 40948642Meta-AnalysisFull text (PMC)
Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis of randomized controlled trials.
Kashbour Muataz, Shata Abdelrahman, Wagdy Mohamed et al. · Naunyn Schmiedebergs Arch Pharmacol · 2025
PMID: 40047860Meta-Analysis
Edaravone for patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Huang Shi-Le, Shen Yin-Li, Peng Wen-Yan et al. · Acta Neurol Belg · 2024
PMID: 38347315Meta-Analysis
Edaravone combined with hyperbaric oxygen therapy in delayed encephalopathy after acute carbon monoxide poisoning: A meta-analysis.
Zeng Siyao, Li Yue, Yao Zhipeng et al. · J Clin Neurosci · 2024
PMID: 38986338Meta-Analysis
Safety and Efficacy of Edaravone in Patients with Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-analysis.
Gao Mengxia, Zhu Lingqun, Chang Jingling et al. · Clin Drug Investig · 2023
PMID: 36462105Meta-Analysis
Safety and efficacy of edaravone in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Nourelden Anas Zakarya, Kamal Ibrahim, Hagrass Abdulrahman Ibrahim et al. · Neurol Sci · 2023
PMID: 37249667Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Edaravone (substance)
SNOMED CT
736496005
UMLS CUI
C0070694
RxNorm CUI
1921877
Labeler
Tanabe Pharma America, Inc.

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.