Substance / Medication

Enfuvirtide

Overview

Active Ingredient
enfuvirtide
RxNorm CUI
139896

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Change in HIV-1 DNA tropism despite virological success in patients receiving an enfuvirtide-based regimen.
Charpentier Charlotte, Joly Véronique, Ghosn Jade et al. · J Antimicrob Chemother · 2014
PMID: 24816213RCT
Switch from enfuvirtide to raltegravir in virologically suppressed multidrug-resistant HIV-1-infected patients: a randomized open-label trial.
De Castro Nathalie, Braun Joséphine, Charreau Isabelle et al. · Clin Infect Dis · 2009
PMID: 19757993RCT
Viral failure in HIV-infected patients with long-lasting viral suppression who discontinued enfuvirtide.
Bonjoch Anna, Negredo Eugenia, Puig Jordi et al. · AIDS · 2006
PMID: 16954734RCT
A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats.
Kaminskas Lisa M, Williams Charlotte C, Leong Nathania J et al. · Eur J Pharm Biopharm · 2019
PMID: 30851352Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Enfuvirtide (substance)
SNOMED CT
409127007
UMLS CUI
C0537439
RxNorm CUI
139896

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.