Substance / Medication

Glimepiride

Overview

Active Ingredient
glimepiride
RxNorm CUI
25789

Indications

14.1 Clinical Studies () Glimepiride tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see]. Limitations of Use Glimepiride tablets should not be used for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, as it would not be effective in these settings.

Labeler: NuCare Pharmaceuticals,Inc.Updated: 2026-02-19T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Glimepiride tablets are contraindicated in patients with a history of a hypersensitivity reaction to: 5.2 Warnings and Precautions () Glimepiride or any of the product’s ingredients [see]. Sulfonamide derivatives: Patients who have developed an allergic reaction to sulfonamide derivatives may dev

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

45 trials linked to this intervention

45
Total Trials
0
Recruiting
13
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Effect of glimepiride versus teneligliptin in combination with metformin in type 2 diabetes mellitus patients.
Rasheed Razia Abdul, Venkatraman G, Vijayalakshmi S et al. · Indian J Pharmacol · 2024
PMID: 39687954RCTFull text (PMC)
Incident and recurrent hypoglycaemia with linagliptin and glimepiride over a median of 6 years in the CAROLINA cardiovascular outcome trial.
Rosenstock Julio, Kolkailah Ahmed A, McGuire Darren K et al. · Diabetes Obes Metab · 2023
PMID: 36700416RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Glimepiride (substance)
SNOMED CT
386966003
UMLS CUI
C0061323
RxNorm CUI
25789
Labeler
NuCare Pharmaceuticals,Inc.

Clinical Data

This intervention maps to 10 entities in the Healos knowledge graph.

1
Conditions
4
Biomarkers
3
Specialists
0
Symptoms
45
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.