Substance / Medication

Glutamine

Overview

Active Ingredient
glutamine
RxNorm CUI
4885

Indications

L-glutamine is indicated to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older.

Labeler: ANI Pharmaceuticals, Inc.Updated: 2025-08-07T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Glutamine prevents diarrhea in colorectal cancer patients undergoing chemotherapy or chemoradiotherapy: a meta-analysis.
Chen Lijuan, Wang Duo, Meng Chang et al. · BMC Gastroenterol · 2025
PMID: 41053591Meta-AnalysisFull text (PMC)
Glutamine Peptides: Preparation, Analysis, Applications, and Their Role in Intestinal Barrier Protection.
Wang Jinyu, He Yating, Liu Zedan et al. · Nutrients · 2025
PMID: 40290078Meta-AnalysisFull text (PMC)
Role of ammonia and glutamine in the pathogenesis and progression of metabolic dysfunction-associated steatotic liver disease: A systematic review.
Njei Basile, Al-Ajlouni Yazan A, Ameyaw Prince et al. · J Gastroenterol Hepatol · 2024
PMID: 38763916Meta-Analysis
A systematic review and meta-analysis of clinical trials on the effects of glutamine supplementation on gut permeability in adults.
Abbasi Fatemeh, Haghighat Lari Mohammad Mehdi, Khosravi Gholamreza Reza et al. · Amino Acids · 2024
PMID: 39397201Meta-AnalysisFull text (PMC)
Enteral glutamine supplements for patients with severe burns: A systematic review and meta-analysis.
Yue Han-Yang, Wang Yu, Zeng Jun et al. · Chin J Traumatol · 2024
PMID: 37460347Meta-AnalysisFull text (PMC)
Effectiveness of glutamine for the treatment of radiodermatitis in cancer patients: a meta-analysis of randomized controlled trials.
Chang Hsu-Chieh, Huang Wen-Yen, Chen Po-Huang et al. · Support Care Cancer · 2024
PMID: 38427125Meta-Analysis
Glutamine Supplementation on Burn Patients: A Systematic Review and Meta-analysis.
Tao Wei, Xu Gang, Zhou Jie et al. · J Burn Care Res · 2024
PMID: 38243579Meta-Analysis
The Efficacy of Glutamine Supplementation in Severe Adult Burn Patients: A Systematic Review With Trial Sequential Meta-Analysis.
Ortiz-Reyes Luis, Lee Zheng-Yii, Chin Han Lew Charles et al. · Crit Care Med · 2023
PMID: 37114912Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Glutamine (substance)
SNOMED CT
25761002
UMLS CUI
C0017797
RxNorm CUI
4885
Labeler
ANI Pharmaceuticals, Inc.

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

2
Conditions
1
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.