Substance / Medication

Hydroxyzine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

63 trials linked to this intervention

63
Total Trials
5
Recruiting
21
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Brief psychotic disorder after abrupt withdrawal of hydroxyzine hydrochloride.
Bock Oliver, Wenzel Claudia, Herrmann Julian et al. · J Clin Psychopharmacol · 2014
PMID: 24875068Case Report
Hydroxyzine hydrochloride in familial restless legs syndrome.
Di Fabio Roberto, Casali Carlo, Vadalà Rita et al. · Can J Neurol Sci · 2010
PMID: 20481280Case Report
[A case of acute urticaria from hydroxyzine hydrochloride used for preanesthetic medication].
Urabe K, Fujii K, Tezuka M et al. · Masui · 2000
PMID: 10998884Case Report
Effect of intravenous administration of hydroxyzine hydrochloride on intrathecal morphine-induced pruritus after cesarean section.
Uchimura Shuji, Yano Takeshi, Tsuneyoshi Isao · Minerva Anestesiol · 2024
PMID: 37987995Other
Vanadium-Containing Anionic Chelate for Spectrophotometric Determination of Hydroxyzine Hydrochloride in Pharmaceuticals.
Kirova Gergana Kirilova, Velkova Zdravka Yancheva, Delchev Vassil Borisov et al. · Molecules · 2023
PMID: 36985455OtherFull text (PMC)
Fixed drug eruption to aripiprazole, cetirizine, and hydroxyzine hydrochloride.
Diaz-Ramos Nicole, Nazario Sylvette, Malinow-Maceo Iona · Ann Allergy Asthma Immunol · 2023
PMID: 36521786Other
Real-World, Non-Interventional, Observational Study of Hydroxyzine Hydrochloride in Chronic Pruritus: a Prospective, Non-Comparative Study.
Thomas Jayakar, Saple Dattatray G, Jerajani Hemangi R et al. · Dermatol Ther (Heidelb) · 2019
PMID: 30949959OtherFull text (PMC)
Development and validation of a method for the analysis of hydroxyzine hydrochloride in extracellular solution used in in vitro preclinical safety studies.
Briône Willy, Brekelmans Mari, Eijndhoven Freek van et al. · J Pharm Biomed Anal · 2015
PMID: 26163869Other
In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery.
Zaki Rizkalla Christianne Mounir, latif Aziz Randa, Soliman Iman Ibrahim · AAPS PharmSciTech · 2011
PMID: 21800216PreclinicalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Hydroxyzine hydrochloride (substance)
SNOMED CT
83945003
UMLS CUI
C0600110

Clinical Data

This intervention maps to 8 entities in the Healos knowledge graph.

3
Conditions
1
Biomarkers
2
Specialists
0
Symptoms
63
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.