Substance / Medication

Lenalidomide

Overview

Active Ingredient
lenalidomide
RxNorm CUI
342369
Labeler: Devatis Inc.Updated: 2026-02-03T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

WARNING: EMBRYO-FETAL TOXICITY, HEMATOLOGIC TOXICITY, and VENOUS and ARTERIAL THROMBOEMBOLISM Embryo-Fetal Toxicity 5.1 17 [see Warnings and Precautions (), and Medication Guide ()]. Do not use lenalidomide capsules during pregnancy. Lenalidomide, a thalidomide analogue, caused limb abnormalities in

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Multiple myeloma refractory to lenalidomide: A systematic literature review of trials and real-world evidence.
Hartley-Brown Monique A, Weisel Katja, Bitetti Jacopo et al. · Br J Haematol · 2024
PMID: 39031440Meta-Analysis
Effect of prior lenalidomide or daratumumab exposure on hematopoietic stem cell collection and reconstitution in multiple myeloma.
Duan Hongpeng, Jiang Qiuhui, Liu Long et al. · Ann Hematol · 2024
PMID: 38448787Meta-Analysis
Lenalidomide or Thalidomide for Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma? An Overview of Systematic Reviews.
Visacri Marília Berlofa, Ribeiro Mayra Carvalho, Komoda Denis Satoshi et al. · Value Health Reg Issues · 2024
PMID: 38718736Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Lenalidomide (substance)
SNOMED CT
421471009
UMLS CUI
C1144149
RxNorm CUI
342369
Labeler
Devatis Inc.

Clinical Data

This intervention maps to 3 entities in the Healos knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.