Substance / Medication

Methysergide

Overview

Active Ingredient
methysergide
RxNorm CUI
6911

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Methysergide-induced valvular heart disease: a report of 2 cases.
Alizzi Ali M, Al-Masri Ayman H, Murton Mark M et al. · Heart Surg Forum · 2006
PMID: 17099974Case Report
Methysergide-induced scleroderma-like changes of the legs.
Kluger N, Girard C, Bessis D et al. · Br J Dermatol · 2005
PMID: 16029366Case Report
Methysergide-induced retroperitoneal fibrosis and pericardial effusion.
Cai F Z, Tesar P, Klestov A · Intern Med J · 2004
PMID: 15151680Case Report
Silent myocardial ischaemia following methysergide overdose.
Fisher A A, Le Couteur D G · Aust N Z J Med · 2000
PMID: 11198591Case Report
Intermittent hypercapnia-induced phrenic long-term depression is revealed after serotonin receptor blockade with methysergide in anaesthetized rats.
Valic Maja, Pecotic Renata, Pavlinac Dodig Ivana et al. · Exp Physiol · 2016
PMID: 26621042Preclinical
Sodium intake, brain c-Fos protein and gastric emptying in cell-dehydrated rats treated with methysergide into the lateral parabrachial nucleus.
David Richard B, Roncari Camila F, Lauar Mariana R et al. · Physiol Behav · 2015
PMID: 26171591Preclinical
Methysergide attenuates systemic burn edema in rats.
Hernekamp Jochen Frederick, Hu S, Schmidt K et al. · Microvasc Res · 2013
PMID: 23669653Preclinical
Effect of methysergide on pudendal inhibition of micturition reflex in cats.
Matsuta Yosuke, Schwen Zeyad, Mally Abhijith D et al. · Exp Neurol · 2013
PMID: 23688680PreclinicalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Methysergide (substance)
SNOMED CT
387044000
UMLS CUI
C0025842
RxNorm CUI
6911

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.