Substance / Medication

Nizatidine

Overview

Active Ingredient
nizatidine
RxNorm CUI
42319

Indications

Nizatidine capsules are indicated for up to 8 weeks for the treatment of active duodenal ulcer. In most patients, the ulcer will heal within 4 weeks. Nizatidine capsules are indicated for maintenance therapy for duodenal ulcer patients at a reduced dosage of 150 mg h.s. after healing of an active duodenal ulcer. The consequences of continuous therapy with nizatidine for longer than 1 year are not known. Nizatidine capsules are indicated for up to 12 weeks for the treatment of endoscopically diag

Labeler: Epic Pharma, LLCUpdated: 2025-01-02T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

2 2 Nizatidine capsules are contraindicated in patients with known hypersensitivity to the drug. Because cross sensitivity in this class of compounds has been observed, H-receptor antagonists, including nizatidine, should not be administered to patients with a history of hypersensitivity to other H-

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Formulation, optimization, and evaluation of raft-forming formulations containing Nizatidine.
Darwish Manal K M, Abu El-Enin Amal S M, Mohammed Kamilia H A · Drug Dev Ind Pharm · 2019
PMID: 30638411RCT
The effects of nizatidine on transient lower esophageal sphincter relaxations (TLESRs) and acid reflux in healthy subjects.
Iwakiri Katsuhiko, Kawami Noriyuki, Sano Hirohito et al. · J Smooth Muscle Res · 2011
PMID: 22374468RCT
Does the use of nizatidine, as a pro-kinetic agent, improve gastric emptying in patients post-oesophagectomy?
Simpson Paul J, Ooi Corinne, Chong Jennifer et al. · J Gastrointest Surg · 2009
PMID: 18979143RCT
Effect of the H2 receptor antagonist nizatidine on xerostomia in patients with primary Sjögren's syndrome.
Kasama Tsuyoshi, Shiozawa Fumitaka, Isozaki Takeo et al. · Mod Rheumatol · 2008
PMID: 18478182RCT
Nizatidine and gastric emptying in functional dyspepsia.
Koskenpato Jari, Punkkinen Jari Matti, Kairemo Kalevi et al. · Dig Dis Sci · 2008
PMID: 17682943RCT
Weight gain management in patients with schizophrenia during treatment with olanzapine in association with nizatidine.
Assunção Sheila Seleri Marques, Ruschel Sandra Inês, Rosa Lucena de Cássia Rodrigues et al. · Braz J Psychiatry · 2006
PMID: 17242805RCT
Extraction of ranitidine and nizatidine with using imidazolium ionic liquids prior spectrophotometric and chromatographic detection.
Kiszkiel Ilona, Starczewska Barbara, Leśniewska Barbara et al. · J Pharm Biomed Anal · 2015
PMID: 25498149Observational
Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: application to the analysis of ranitidine and its metabolites in human volunteers.
Ashiru Diane A I, Patel Rajesh, Basit Abdul W · J Chromatogr B Analyt Technol Biomed Life Sci · 2007
PMID: 18006395Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Nizatidine (substance)
SNOMED CT
386887009
UMLS CUI
C0085154
RxNorm CUI
42319
Labeler
Epic Pharma, LLC

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.