Substance / Medication

Pitolisant

Overview

Active Ingredient
pitolisant
RxNorm CUI
2197878

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Pitolisant for treating patients with narcolepsy.
Li Shuang, Yang Junyi · Expert Rev Clin Pharmacol · 2020
PMID: 31937172Meta-Analysis
A proof-of-concept study of pitolisant for excessive daytime sleepiness in patients with Prader-Willi syndrome.
Revana Amee, Bhattacharjee Rakesh, Miller Jennifer L et al. · J Clin Sleep Med · 2025
PMID: 40605372RCTFull text (PMC)
Pitolisant 40 mg for excessive daytime sleepiness in obstructive sleep apnea patients treated or not by CPAP: Randomised phase 3 study.
Dauvilliers Yves, Craig Sonya Elizabeth, Bonsignore Maria R et al. · J Sleep Res · 2025
PMID: 39377364RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pitolisant (substance)
SNOMED CT
716308007
UMLS CUI
C3529928
RxNorm CUI
2197878

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.