Substance / Medication

Pralidoxime iodide

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Outcomes and Practices of Endotracheal Intubation Using the Glasgow Coma Scale in Acute Non-Traumatic Poisoning: A Systematic Review and Meta-Analysis of Proportions.
Nanah Abdelrahman, Abdeljaleel Fatima, Matsubara Júlio Ken et al. · J Intensive Care Med · 2025
PMID: 39150325Meta-Analysis
Extracorporeal Membrane Oxygenation in Intoxication and Overdoses: A Systematic Review.
Maier Sven, Rösner Lisa, Saemann Lars et al. · Thorac Cardiovasc Surg · 2024
PMID: 36940708Meta-Analysis
Gastrointestinal decontamination using oil-based solutions in patients with acute aluminum phosphide poisoning: a systematic review and meta-analysis.
Hafez Amal S A F, Elgazzar Fatma M, Sobh Zahraa K et al. · Crit Rev Toxicol · 2024
PMID: 38656260Meta-Analysis
Chlorfenapyr poisoning: a systematic review.
Comstock Grant Thomas, Nguyen HoanVu, Bronstein Alvin et al. · Clin Toxicol (Phila) · 2024
PMID: 38984827Meta-Analysis
Pediatric poisoning deaths in Saudi Arabia: A systematic review.
Almutairi Saad A, Alsaleem Jassim Hijji, Alrashed Mahdi A et al. · Leg Med (Tokyo) · 2023
PMID: 36395600Meta-Analysis
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup.
Ghannoum Marc, Gosselin Sophie, Hoffman Robert S et al. · Crit Care · 2023
PMID: 36765419Meta-AnalysisFull text (PMC)
[Three cases of organophosphate poisoning treated with pralidoxime iodide and whole-bowel irrigation].
Fujino Yasuhisa, Inoue Yoshihiro, Onodera Makoto et al. · Chudoku Kenkyu · 2004
PMID: 15495687Case Report
Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM).
Sakurada Koichi, Ikegaya Hiroshi, Ohta Hikoto et al. · Toxicol Lett · 2006
PMID: 16971069Preclinical
Pralidoxime iodide (2-pAM) penetrates across the blood-brain barrier.
Sakurada Koichi, Matsubara Kazuo, Shimizu Keiko et al. · Neurochem Res · 2003
PMID: 12938863Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pralidoxime iodide (substance)
SNOMED CT
1186942004
UMLS CUI
C0138210

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.