Substance / Medication

Pyridoxal phosphate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Stability-indicating HPLC-PDA assay for simultaneous determination of paracetamol, thiamine and pyridoxal phosphate in tablet formulations.
Ali Amir, Athar Muhammad Makshoof, Ahmed Mahmood et al. · Acta Pharm · 2019
PMID: 31259722Observational
Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor.
Kim Yong-Chul, Lee Jung-Sun, Sak Katrin et al. · Biochem Pharmacol · 2005
PMID: 15913566ObservationalFull text (PMC)
Pyridoxal phosphate is better than pyridoxine for controlling idiopathic intractable epilepsy.
Wang H-S, Kuo M-F, Chou M-L et al. · Arch Dis Child · 2005
PMID: 15851435ObservationalFull text (PMC)
Hepatocellular Carcinoma: A Critical Complication in Patients Treated with Pyridoxal Phosphate.
Brands Marion M, de Puyraimond Chloé, Gospe Sidney M et al. · Neuropediatrics · 2026
PMID: 41429136Case ReportFull text (PMC)
Lysine Restriction and Pyridoxal Phosphate Administration in a NADK2 Patient.
Tort Frederic, Ugarteburu Olatz, Torres Maria Angeles et al. · Pediatrics · 2016
PMID: 27940755Case Report
Seizures with decreased levels of pyridoxal phosphate in cerebrospinal fluid.
Goyal Monisha, Fequiere Pierre R, McGrath Tony M et al. · Pediatr Neurol · 2013
PMID: 23419474Case Report
Pyridoxal phosphate-dependent neonatal epileptic encephalopathy.
Bagci S, Zschocke J, Hoffmann G F et al. · Arch Dis Child Fetal Neonatal Ed · 2008
PMID: 18296573Case Report
A successful treatment with pyridoxal phosphate for West syndrome in hypophosphatasia.
Yamamoto Hitoshi, Sasamoto Yuka, Miyamoto Yusaku et al. · Pediatr Neurol · 2004
PMID: 15033207Case Report

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Pyridoxal phosphate (substance)
SNOMED CT
259663004
UMLS CUI
C0034266

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.