Substance / Medication

Quetiapine

Overview

Active Ingredient
quetiapine
RxNorm CUI
51272
Labeler: Solco Healthcare U.S., LLCUpdated: 2023-10-31T00:00:00.000ZFull label on DailyMed

Boxed Warning

FDA Black Box Warning

Increased Mortality in Elderly Patients with Dementia-Related Psychosis Warnings and Precautions (5.1) [see] Warnings and Precautions (5.1) [see]. Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Quetiapine extended-release tablets

Contraindications

When this intervention should not be used

Hypersensitivity to quetiapine or to any excipients in the quetiapine extended-release tablets formulation. Anaphylactic reactions have been reported in patients treated with quetiapine extended-release tablets.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Effect of quetiapine versus haloperidol on delirium severity in hospitalized adults: A systematic review and meta‑analysis.
Zainab Shiza, Fatima Eshal, Khalid Muhammad Salman et al. · Asian J Psychiatr · 2026
PMID: 41483728Meta-Analysis
Metabolic Adverse Effects of Low-Dose Quetiapine: A Systematic Review and Meta-Analysis.
Sonim Pedro, Ferreira Rui M, Lourenço Inês et al. · Acta Psychiatr Scand · 2025
PMID: 40772433Meta-Analysis
Quetiapine, Clozapine, and Pimavanserin Treatment Response in Monogenic Parkinson's Disease Psychosis: A Systematic Review.
Colijn Mark Ainsley · J Neuropsychiatry Clin Neurosci · 2025
PMID: 39034670Meta-Analysis
Insights into the population pharmacokinetics and pharmacodynamics of quetiapine: a systematic review.
Han Lu, Gu Jia-Qin, Mao Jue-Hui et al. · Expert Rev Clin Pharmacol · 2024
PMID: 38108086Meta-Analysis
Research encouraging off-label use of quetiapine: A systematic meta-epidemiological analysis.
Grabitz Peter, Saksone Lana, Schorr Susanne Gabriele et al. · Clin Trials · 2024
PMID: 38284364Meta-Analysis
Effect of quetiapine on inflammation and immunity: a systematic review.
Ferrari Marco, Godio Marco, Martini Stefano et al. · Int J Psychiatry Clin Pract · 2023
PMID: 35913757Meta-Analysis
Effects of quetiapine on sleep: A systematic review and meta-analysis of clinical trials.
Lin Che-Yin, Chiang Cheng-Hen, Tseng Mei-Chih Meg et al. · Eur Neuropsychopharmacol · 2023
PMID: 36463762Meta-Analysis
Is aripiprazole similar to quetiapine for treatment of bipolar depression? Results from meta-analysis of Chinese data.
Tao Hejian, Wang Jiawei, Shen Dong et al. · Front Psychiatry · 2022
PMID: 36159936Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Quetiapine (substance)
SNOMED CT
386850001
UMLS CUI
C0123091
RxNorm CUI
51272
Labeler
Solco Healthcare U.S., LLC

Clinical Data

This intervention maps to 12 entities in the Healos knowledge graph.

7
Conditions
3
Biomarkers
1
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.