Substance / Medication

Quinestradol

SNOMED 420164003 UMLS C0072864

Overview

Active Ingredient

quinestradol

RxNorm CUI

35215

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Menopausal flushing

Malignant tumor of breast

Malignant tumour of prostate

Climacteric flushing

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Leukocytes

LOINC 26464-8

secondary

Cancer Ag 15-3

LOINC 6875-9

primary

Prostate specific Ag

LOINC 2857-1

primary

Clinical Trials

20 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

Study Evaluating Totelle® in Menopausal Symptoms and Sexual Function

NCT00195520Phase 4Completed100 enrolled

Efficacy and Safety Study in Postmenopausal Women to Determine the Lowest Effective Dose for Relief of Moderate to Severe Hot-Flushes

NCT00206622Phase 4Completed425 enrolled

Study of Paxil Use in Menopausal Women

NCT00225914Phase 4Completed64 enrolled

Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia

NCT00227942Phase 4Completed86 enrolled

Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy

NCT00245518Phase 4Completed39 enrolled

View all 20 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Kuntai capsule for the treatment of menopausal symptoms induced by GnRH-a therapy: A systematic review and meta-analysis of randomized controlled trials.

Yu Junhong, Yu Fanya, Zhang Lina et al. · J Ethnopharmacol · 2026

PMID: 41047051Meta-Analysis

The effectiveness of yoga on menopausal symptoms: A systematic review and meta-analysis of randomized controlled trials.

Wang Hongjuan, Liu Yaqian, Kwok Jojo Yan Yan et al. · Int J Nurs Stud · 2025

PMID: 39467491Meta-Analysis

Safety of Fezolinetant for Treatment of Moderate to Severe Vasomotor Symptoms Due to Menopause: Pooled Analysis of Three Randomized Phase 3 Studies.

Kagan Risa, Cano Antonio, Nappi Rossella E et al. · Adv Ther · 2025

PMID: 39739195Meta-AnalysisFull text (PMC)

Fezolinetant and Elinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: A Systematic Review and Meta-analysis.

Menegaz de Almeida Artur, Oliveira Paloma, Lopes Lucca et al. · Obstet Gynecol · 2025

PMID: 39746208Meta-Analysis

Fezolinetant's efficacy and safety in treatment of vasomotor symptoms in postmenopausal women: a meta-analysis and GRADE evaluation of randomized controlled trials.

Allam Abdallah R, Alhateem Mohamed Salah, Mahmoud Abdelrahman Mohamed · Eur J Med Res · 2025

PMID: 39849636Meta-AnalysisFull text (PMC)

Efficacy and safety of elinzanetant in vasomotor symptoms associated with menopause: A meta-analysis of randomized controlled trials.

Sobral Milene Vitória Sampaio, Rocha Paula, Rodrigues Livia Kneipp et al. · Eur J Obstet Gynecol Reprod Biol · 2025

PMID: 39919442Meta-Analysis

Efficacy and safety of fezolinetant and elinzanetant for vasomotor symptoms in postmenopausal women: A systematic review and meta-analysis.

de Oliveira Helen Michaela, Diaz Camilo André Viana, Barbosa Lucas Mendes et al. · Maturitas · 2025

PMID: 39987726Meta-Analysis

Effect of physical activity on sleep in women experiencing vasomotor symptoms during menopause: a systematic review and meta-analysis.

Corrêa Adriano Bruno, Bardella Mateus do Carmo, da Silva Arthur Polveiro et al. · Maturitas · 2025

PMID: 40288155Meta-Analysis

A Meta-Analysis: Anti-Inflammatory Medicinal Plants for Age-Related Menopause-Like Symptoms and Psychological Problems in Breast Cancer and Healthy Perimenopausal Women.

Zhang Fan, Yang Dianhui · BJOG · 2025

PMID: 40329882Meta-Analysis

Pharmacological Treatments for Menopausal Vasomotor Symptoms: A Systematic Review and Bayesian Network Meta-Analysis of Efficacy and Safety.

Oliveira Amador Wellgner Fernandes, Saraiva Cainã Araújo, Ruelas Mariano Gallo et al. · Eur J Obstet Gynecol Reprod Biol · 2025

PMID: 40592206Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Medical Oncology Physician

Internal Medicine — Medical Oncology

Surgery

Urology

Health Goals

Goals connected through associated conditions

Screen for Cancer Risk

Quick Facts

Type: Substance / Medication
Fully Specified Name: Quinestradol (substance)
SNOMED CT: 420164003
UMLS CUI: C0072864
RxNorm CUI: 35215

Clinical Data

This intervention maps to 11 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.